High allergic reactivity in a tropical environment
Summary The prevalence of atopic disease in tropical populations is often considered to be low, and this has been attributed to an immunological modulating effect of intestinal helminthiasis. We, however, report that the frequency of positive allergic history and skin‐test reactivity to groups of ma...
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| Veröffentlicht in: | Clinical allergy 1984-05, Vol.14 (3), p.233-240 |
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| container_title | Clinical allergy |
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| creator | LYNCH, NEIL R. Di PRISCO-FUENMAYOR, MARÍA C. |
| description | Summary
The prevalence of atopic disease in tropical populations is often considered to be low, and this has been attributed to an immunological modulating effect of intestinal helminthiasis. We, however, report that the frequency of positive allergic history and skin‐test reactivity to groups of major environmental allergens is extremely high (43 and 63% respectively) in children in Caracas, Venezuela (Lat. 10°N).
These values were statistically significantly greater than in a group of children with a similar age and sex distribution studied in parallel, but having limited or no contact with a tropical environment (29 and 37% respectively). The two groups differed with respect to the sporadic and light intestinal helminthic infections (such as ascariasis) experienced by the Venezuelans, compared to rare contact in the ‘non‐tropical’ group. This was probably the cause of the increased total serum IgE levels of the former children (369 vs 68 iu/ml), and possibly, therefore, their higher allergic reactivity. |
| doi_str_mv | 10.1111/j.1365-2222.1984.tb02202.x |
| format | Article |
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The prevalence of atopic disease in tropical populations is often considered to be low, and this has been attributed to an immunological modulating effect of intestinal helminthiasis. We, however, report that the frequency of positive allergic history and skin‐test reactivity to groups of major environmental allergens is extremely high (43 and 63% respectively) in children in Caracas, Venezuela (Lat. 10°N).
These values were statistically significantly greater than in a group of children with a similar age and sex distribution studied in parallel, but having limited or no contact with a tropical environment (29 and 37% respectively). The two groups differed with respect to the sporadic and light intestinal helminthic infections (such as ascariasis) experienced by the Venezuelans, compared to rare contact in the ‘non‐tropical’ group. This was probably the cause of the increased total serum IgE levels of the former children (369 vs 68 iu/ml), and possibly, therefore, their higher allergic reactivity.</description><identifier>ISSN: 0954-7894</identifier><identifier>ISSN: 0009-9090</identifier><identifier>EISSN: 1365-2222</identifier><identifier>DOI: 10.1111/j.1365-2222.1984.tb02202.x</identifier><identifier>PMID: 6733888</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Adolescent ; Allergic diseases ; Biological and medical sciences ; Child ; Female ; General aspects ; Helminthiasis - immunology ; Humans ; Hypersensitivity - epidemiology ; Hypersensitivity, Immediate - epidemiology ; Immunoglobulin E - immunology ; Immunopathology ; Male ; Medical sciences ; Other localizations ; Prevention and actions ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Skin Tests ; Specific populations (family, woman, child, elderly...) ; Tropical medicine ; Venezuela</subject><ispartof>Clinical allergy, 1984-05, Vol.14 (3), p.233-240</ispartof><rights>1984 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5723-d8a30f314252fe58eac1a6372869689d1d3ef47a69acc738215c766e80a4d5003</citedby><cites>FETCH-LOGICAL-c5723-d8a30f314252fe58eac1a6372869689d1d3ef47a69acc738215c766e80a4d5003</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1365-2222.1984.tb02202.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1365-2222.1984.tb02202.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27903,27904,45553,45554</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=9685964$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6733888$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>LYNCH, NEIL R.</creatorcontrib><creatorcontrib>Di PRISCO-FUENMAYOR, MARÍA C.</creatorcontrib><title>High allergic reactivity in a tropical environment</title><title>Clinical allergy</title><addtitle>Clin Allergy</addtitle><description>Summary
The prevalence of atopic disease in tropical populations is often considered to be low, and this has been attributed to an immunological modulating effect of intestinal helminthiasis. We, however, report that the frequency of positive allergic history and skin‐test reactivity to groups of major environmental allergens is extremely high (43 and 63% respectively) in children in Caracas, Venezuela (Lat. 10°N).
These values were statistically significantly greater than in a group of children with a similar age and sex distribution studied in parallel, but having limited or no contact with a tropical environment (29 and 37% respectively). The two groups differed with respect to the sporadic and light intestinal helminthic infections (such as ascariasis) experienced by the Venezuelans, compared to rare contact in the ‘non‐tropical’ group. This was probably the cause of the increased total serum IgE levels of the former children (369 vs 68 iu/ml), and possibly, therefore, their higher allergic reactivity.</description><subject>Adolescent</subject><subject>Allergic diseases</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Female</subject><subject>General aspects</subject><subject>Helminthiasis - immunology</subject><subject>Humans</subject><subject>Hypersensitivity - epidemiology</subject><subject>Hypersensitivity, Immediate - epidemiology</subject><subject>Immunoglobulin E - immunology</subject><subject>Immunopathology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Other localizations</subject><subject>Prevention and actions</subject><subject>Public health. Hygiene</subject><subject>Public health. Hygiene-occupational medicine</subject><subject>Skin Tests</subject><subject>Specific populations (family, woman, child, elderly...)</subject><subject>Tropical medicine</subject><subject>Venezuela</subject><issn>0954-7894</issn><issn>0009-9090</issn><issn>1365-2222</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1984</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkEtLAzEUhYMoWh8_QRhE3M2Yx-TlQij1UUUUQRHchJjJaOp0pibT2v57M3To3rvJ4px7cu4HwAmCGYpzPskQYTTFcTIkRZ61HxBjiLPlFhhspG0wgJLmKRcy3wP7IUwghIRKsQt2GSdECDEAeOw-vxJdVdZ_OpN4q03rFq5dJa5OdNL6ZuaMrhJbL5xv6qmt20OwU-oq2KP-PQCvN9cvo3H68HR7Nxo-pIZyTNJCaAJLgnJMcWmpiMlIM8KxYJIJWaCC2DLnmkltDCcCI2o4Y1ZAnRc0Nj0AZ-vcmW9-5ja0auqCsVWla9vMgxIRBSRMRuPF2mh8E4K3pZp5N9V-pRBUHTA1UR0V1VFRHTDVA1PLuHzc_zL_mNpis9oTivppr-sQQZRe18aFjS2eQiXLo-1ybft1lV39o4AaXQ8xITEgXQe40NrlJkD7764Kp-rt8Vbdv7B3xN-f1RX5A_ZjlUU</recordid><startdate>198405</startdate><enddate>198405</enddate><creator>LYNCH, NEIL R.</creator><creator>Di PRISCO-FUENMAYOR, MARÍA C.</creator><general>Blackwell Publishing Ltd</general><general>Blackwell</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198405</creationdate><title>High allergic reactivity in a tropical environment</title><author>LYNCH, NEIL R. ; Di PRISCO-FUENMAYOR, MARÍA C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5723-d8a30f314252fe58eac1a6372869689d1d3ef47a69acc738215c766e80a4d5003</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1984</creationdate><topic>Adolescent</topic><topic>Allergic diseases</topic><topic>Biological and medical sciences</topic><topic>Child</topic><topic>Female</topic><topic>General aspects</topic><topic>Helminthiasis - immunology</topic><topic>Humans</topic><topic>Hypersensitivity - epidemiology</topic><topic>Hypersensitivity, Immediate - epidemiology</topic><topic>Immunoglobulin E - immunology</topic><topic>Immunopathology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Other localizations</topic><topic>Prevention and actions</topic><topic>Public health. Hygiene</topic><topic>Public health. Hygiene-occupational medicine</topic><topic>Skin Tests</topic><topic>Specific populations (family, woman, child, elderly...)</topic><topic>Tropical medicine</topic><topic>Venezuela</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>LYNCH, NEIL R.</creatorcontrib><creatorcontrib>Di PRISCO-FUENMAYOR, MARÍA C.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical allergy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>LYNCH, NEIL R.</au><au>Di PRISCO-FUENMAYOR, MARÍA C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>High allergic reactivity in a tropical environment</atitle><jtitle>Clinical allergy</jtitle><addtitle>Clin Allergy</addtitle><date>1984-05</date><risdate>1984</risdate><volume>14</volume><issue>3</issue><spage>233</spage><epage>240</epage><pages>233-240</pages><issn>0954-7894</issn><issn>0009-9090</issn><eissn>1365-2222</eissn><abstract>Summary
The prevalence of atopic disease in tropical populations is often considered to be low, and this has been attributed to an immunological modulating effect of intestinal helminthiasis. We, however, report that the frequency of positive allergic history and skin‐test reactivity to groups of major environmental allergens is extremely high (43 and 63% respectively) in children in Caracas, Venezuela (Lat. 10°N).
These values were statistically significantly greater than in a group of children with a similar age and sex distribution studied in parallel, but having limited or no contact with a tropical environment (29 and 37% respectively). The two groups differed with respect to the sporadic and light intestinal helminthic infections (such as ascariasis) experienced by the Venezuelans, compared to rare contact in the ‘non‐tropical’ group. This was probably the cause of the increased total serum IgE levels of the former children (369 vs 68 iu/ml), and possibly, therefore, their higher allergic reactivity.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>6733888</pmid><doi>10.1111/j.1365-2222.1984.tb02202.x</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
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| ispartof | Clinical allergy, 1984-05, Vol.14 (3), p.233-240 |
| issn | 0954-7894 0009-9090 1365-2222 |
| language | eng |
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| source | MEDLINE; Wiley Online Library All Journals; Alma/SFX Local Collection |
| subjects | Adolescent Allergic diseases Biological and medical sciences Child Female General aspects Helminthiasis - immunology Humans Hypersensitivity - epidemiology Hypersensitivity, Immediate - epidemiology Immunoglobulin E - immunology Immunopathology Male Medical sciences Other localizations Prevention and actions Public health. Hygiene Public health. Hygiene-occupational medicine Skin Tests Specific populations (family, woman, child, elderly...) Tropical medicine Venezuela |
| title | High allergic reactivity in a tropical environment |
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