HIGH PEEP DECREASES HYALINE MEMBRANE FORMATION IN SURFACTANT DEFICIENT LUNGS

Lung lav age was performed in 16 anaesthetized rabbits to produce surfactant-deficient lungs. This resulted in alveolar collapse, an arterial Po2 of less than 15kPa on 100% oxygen and an inflection point on the inspirator/ limb of the pressure-volume curve at an airway pressure of 8–10 mm Hg. One gr...

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