High‐grade mantle zone lymphoma
A 66‐year‐old man with a 6‐month history of sweating at night, generalized lymphadenopathy, hepatosplenomegaly, and paraproteinemia was diagnosed to have a Stage IV mantle zone lymphoma (MZL), which behaved aggressively. The neoplasm rapidly disseminated to extranodal sites—the skin, lungs, pleural...
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| Veröffentlicht in: | Cancer 1987-12, Vol.60 (11), p.2717-2720 |
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| container_issue | 11 |
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| container_title | Cancer |
| container_volume | 60 |
| creator | Ellison, Douglas J. Turner, Roderick R. van Antwerp, Randy Martin, Sue Ellen Nathwani, Bharat N. |
| description | A 66‐year‐old man with a 6‐month history of sweating at night, generalized lymphadenopathy, hepatosplenomegaly, and paraproteinemia was diagnosed to have a Stage IV mantle zone lymphoma (MZL), which behaved aggressively. The neoplasm rapidly disseminated to extranodal sites—the skin, lungs, pleural cavity, and the central nervous system. The neoplasm did not respond to initial double‐agent chemotherapy, but it did partially respond to multi‐agent chemotherapy. In addition, the neoplasm had histopathologic features not reported previously in MZL—vascular invasion, massive extranodal infiltration, high mitotic count, and convoluted nuclei. |
| doi_str_mv | 10.1002/1097-0142(19871201)60:11<2717::AID-CNCR2820601123>3.0.CO;2-K |
| format | Article |
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The neoplasm rapidly disseminated to extranodal sites—the skin, lungs, pleural cavity, and the central nervous system. The neoplasm did not respond to initial double‐agent chemotherapy, but it did partially respond to multi‐agent chemotherapy. In addition, the neoplasm had histopathologic features not reported previously in MZL—vascular invasion, massive extranodal infiltration, high mitotic count, and convoluted nuclei.</description><identifier>ISSN: 0008-543X</identifier><identifier>EISSN: 1097-0142</identifier><identifier>DOI: 10.1002/1097-0142(19871201)60:11<2717::AID-CNCR2820601123>3.0.CO;2-K</identifier><identifier>PMID: 3677007</identifier><identifier>CODEN: CANCAR</identifier><language>eng</language><publisher>New York: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Aged ; Biological and medical sciences ; Hematologic and hematopoietic diseases ; Humans ; Leukemias. Malignant lymphomas. Malignant reticulosis. 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The neoplasm rapidly disseminated to extranodal sites—the skin, lungs, pleural cavity, and the central nervous system. The neoplasm did not respond to initial double‐agent chemotherapy, but it did partially respond to multi‐agent chemotherapy. In addition, the neoplasm had histopathologic features not reported previously in MZL—vascular invasion, massive extranodal infiltration, high mitotic count, and convoluted nuclei.</description><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Hematologic and hematopoietic diseases</subject><subject>Humans</subject><subject>Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis</subject><subject>Lung - pathology</subject><subject>Lymphoma, Non-Hodgkin - drug therapy</subject><subject>Lymphoma, Non-Hodgkin - pathology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Skin - pathology</subject><issn>0008-543X</issn><issn>1097-0142</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1987</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkN1Kw0AQhRdRav15BKGCiF6kzuwmu0kVQeJfUSyIghfCsE02NZI0Ndsi9cpH8Bl9EhNaC3oheDUczpnD4WPsFKGNAPwAIVAOoMv3MPAVcsB9CR3EI65QdTon3VMnvAlvuc9BAiIXx6IN7bB3yJ2rJdZcvC-zJgD4jueKh1W2Zu1zJRX3RIM1hFSqEk22fZkOnj7fPwaljk0r18NxZlpvxdC0smk-eipyvcFWEp1Zszm_6-z-_OwuvHSuexfd8OTaiVyUwkm4iI0HmOhExVFfGlUJkJ6nZCA1avDdIABfuT7ooK-9wMTCGJ7049hoLwKxznZnvaOyeJkYO6Y8tZHJMj00xcSSjwgqEFgFH2fBqCysLU1CozLNdTklBKoJUo2AagT0TZBkZSHVBIkqgvSTIAkCCnvE6aqq35rvmPRzEy_K58gqf2fuaxvpLCn1MErtIqZcLpVfxwaz2Guamek_J_658JcjvgDQzZnj</recordid><startdate>19871201</startdate><enddate>19871201</enddate><creator>Ellison, Douglas J.</creator><creator>Turner, Roderick R.</creator><creator>van Antwerp, Randy</creator><creator>Martin, Sue Ellen</creator><creator>Nathwani, Bharat N.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley-Liss</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19871201</creationdate><title>High‐grade mantle zone lymphoma</title><author>Ellison, Douglas J. ; Turner, Roderick R. ; van Antwerp, Randy ; Martin, Sue Ellen ; Nathwani, Bharat N.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4163-f23de501faf7dcb6e750106557696a1a08499087480a9ba59ed3ee2fbddea5c03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1987</creationdate><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Hematologic and hematopoietic diseases</topic><topic>Humans</topic><topic>Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis</topic><topic>Lung - pathology</topic><topic>Lymphoma, Non-Hodgkin - drug therapy</topic><topic>Lymphoma, Non-Hodgkin - pathology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Skin - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ellison, Douglas J.</creatorcontrib><creatorcontrib>Turner, Roderick R.</creatorcontrib><creatorcontrib>van Antwerp, Randy</creatorcontrib><creatorcontrib>Martin, Sue Ellen</creatorcontrib><creatorcontrib>Nathwani, Bharat N.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Cancer</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ellison, Douglas J.</au><au>Turner, Roderick R.</au><au>van Antwerp, Randy</au><au>Martin, Sue Ellen</au><au>Nathwani, Bharat N.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>High‐grade mantle zone lymphoma</atitle><jtitle>Cancer</jtitle><addtitle>Cancer</addtitle><date>1987-12-01</date><risdate>1987</risdate><volume>60</volume><issue>11</issue><spage>2717</spage><epage>2720</epage><pages>2717-2720</pages><issn>0008-543X</issn><eissn>1097-0142</eissn><coden>CANCAR</coden><abstract>A 66‐year‐old man with a 6‐month history of sweating at night, generalized lymphadenopathy, hepatosplenomegaly, and paraproteinemia was diagnosed to have a Stage IV mantle zone lymphoma (MZL), which behaved aggressively. The neoplasm rapidly disseminated to extranodal sites—the skin, lungs, pleural cavity, and the central nervous system. The neoplasm did not respond to initial double‐agent chemotherapy, but it did partially respond to multi‐agent chemotherapy. In addition, the neoplasm had histopathologic features not reported previously in MZL—vascular invasion, massive extranodal infiltration, high mitotic count, and convoluted nuclei.</abstract><cop>New York</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>3677007</pmid><doi>10.1002/1097-0142(19871201)60:11<2717::AID-CNCR2820601123>3.0.CO;2-K</doi><tpages>4</tpages></addata></record> |
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| ispartof | Cancer, 1987-12, Vol.60 (11), p.2717-2720 |
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| language | eng |
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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Aged Biological and medical sciences Hematologic and hematopoietic diseases Humans Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lung - pathology Lymphoma, Non-Hodgkin - drug therapy Lymphoma, Non-Hodgkin - pathology Male Medical sciences Skin - pathology |
| title | High‐grade mantle zone lymphoma |
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