Effect of captopril on intrarenal blood flow

The inhibition of the renin-angiotensin system by captopril was used in pentobarbital-anesthetized dogs to confirm that the vasoconstrictive action of endorenally synthesized angiotensin II predominates on the efferent glomerular arteriole. Ozolinone is a loop diuretic with two isomers. Only (−)-ozo...

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Veröffentlicht in:	The American journal of medicine 1984-05, Vol.76 (5), p.53-57
Hauptverfasser:	Imbs, Jean Louis, Schmidt, Mariette, Giesen, Eva-Maria, Schwartz, Jean
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Captopril - pharmacology Diuresis - drug effects Diuretics - pharmacology Dogs Furosemide - therapeutic use Glomerular Filtration Rate - drug effects Humans Hypertension - drug therapy Kidney Concentrating Ability - drug effects Kidney Glomerulus - blood supply Kidney Glomerulus - drug effects Male Osmolar Concentration Proline - analogs & derivatives Propranolol - therapeutic use Rats Renal Circulation - drug effects Renin - metabolism Renin-Angiotensin System - drug effects Stereoisomerism Thiazoles - pharmacology Vasoconstriction - drug effects
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