Study of ribonucleotide reductase in cells infected with six clinical isolates of herpes simplex virus type 2 (HSV-2) with mutations in its larger subunit

Herpes simplex virus type 2 (HSV-2) induces a novel ribonucleotide reductase (RR) composed of two subunits (140 and 38 kDa) in infected cells. Other investigators have developed a monoclonal antibody, A6, against the 140-kDa subunit of RR and have found, in about 1 % of the cases, an inability to de...

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Veröffentlicht in:Virology (New York, N.Y.) N.Y.), 1987-11, Vol.161 (1), p.249-251
Hauptverfasser: Bapat, Ashok R., Grill, Susan P., Nutter, Louise M., Cheng, Yung-Chi
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Sprache:eng
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