Effects of transcutaneous electrical nerve stimulation and aspirin on late somatosensory evoked potentials in normal subjects
The effects on late somatosensory evoked potentials (SEPs) of transcutaneous nerve stimulation (TENS) and aspirin (600 mg), compared with placebo, were studied in 32 young, healthy male and female volunteers. SEPs were produced by electrical stimulation of the median nerve at moderate, non-painful,...
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| Veröffentlicht in: | Pain (Amsterdam) 1984-04, Vol.18 (4), p.377-386 |
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| creator | Ashton, Heather Golding, J.F. Marsh, V.R. Thompson, J.W. |
| description | The effects on late somatosensory evoked potentials (SEPs) of transcutaneous nerve stimulation (TENS) and aspirin (600 mg), compared with placebo, were studied in 32 young, healthy male and female volunteers. SEPs were produced by electrical stimulation of the median nerve at moderate, non-painful, intensities. There was a reduction in the peak-to-peak amplitude of the late components N
1P
2 (N
1 latency: 100–160 msec; P
2 latency: 160–260 msec) of the SEP in all groups over time. TENS but not aspirin produced further significant changes compared with placebo, including a fall in N
1P
2 amplitude, an increase in N
1 latency, and a decrease in the total excursion of the SEP between 25 and 450 msec after stimulus onset. |
| doi_str_mv | 10.1016/0304-3959(84)90050-2 |
| format | Article |
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1P
2 (N
1 latency: 100–160 msec; P
2 latency: 160–260 msec) of the SEP in all groups over time. TENS but not aspirin produced further significant changes compared with placebo, including a fall in N
1P
2 amplitude, an increase in N
1 latency, and a decrease in the total excursion of the SEP between 25 and 450 msec after stimulus onset.</description><identifier>ISSN: 0304-3959</identifier><identifier>EISSN: 1872-6623</identifier><identifier>DOI: 10.1016/0304-3959(84)90050-2</identifier><identifier>PMID: 6610161</identifier><identifier>CODEN: PAINDB</identifier><language>eng</language><publisher>Amsterdam: Elsevier B.V</publisher><subject>Adult ; Afferent Pathways - drug effects ; Analgesics ; Aspirin - pharmacology ; Biological and medical sciences ; Electric Stimulation ; Electric Stimulation Therapy ; Evoked Potentials, Somatosensory - drug effects ; Humans ; Male ; Median Nerve - drug effects ; Medical sciences ; Neuropharmacology ; Nociceptors - drug effects ; Pharmacology. Drug treatments ; Reaction Time - drug effects ; Somatosensory Cortex - drug effects ; Transcutaneous Electric Nerve Stimulation</subject><ispartof>Pain (Amsterdam), 1984-04, Vol.18 (4), p.377-386</ispartof><rights>1984</rights><rights>Lippincott-Raven Publishers.Copyright © Lippincott-Raven Publishers.</rights><rights>1985 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3776-e2f8248ab9e572f72b4c85d4ecb58d04906b5ac833ddde2137cf7389ac71e5e73</citedby><cites>FETCH-LOGICAL-c3776-e2f8248ab9e572f72b4c85d4ecb58d04906b5ac833ddde2137cf7389ac71e5e73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0304-3959(84)90050-2$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8903178$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6610161$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ashton, Heather</creatorcontrib><creatorcontrib>Golding, J.F.</creatorcontrib><creatorcontrib>Marsh, V.R.</creatorcontrib><creatorcontrib>Thompson, J.W.</creatorcontrib><title>Effects of transcutaneous electrical nerve stimulation and aspirin on late somatosensory evoked potentials in normal subjects</title><title>Pain (Amsterdam)</title><addtitle>Pain</addtitle><description>The effects on late somatosensory evoked potentials (SEPs) of transcutaneous nerve stimulation (TENS) and aspirin (600 mg), compared with placebo, were studied in 32 young, healthy male and female volunteers. SEPs were produced by electrical stimulation of the median nerve at moderate, non-painful, intensities. There was a reduction in the peak-to-peak amplitude of the late components N
1P
2 (N
1 latency: 100–160 msec; P
2 latency: 160–260 msec) of the SEP in all groups over time. TENS but not aspirin produced further significant changes compared with placebo, including a fall in N
1P
2 amplitude, an increase in N
1 latency, and a decrease in the total excursion of the SEP between 25 and 450 msec after stimulus onset.</description><subject>Adult</subject><subject>Afferent Pathways - drug effects</subject><subject>Analgesics</subject><subject>Aspirin - pharmacology</subject><subject>Biological and medical sciences</subject><subject>Electric Stimulation</subject><subject>Electric Stimulation Therapy</subject><subject>Evoked Potentials, Somatosensory - drug effects</subject><subject>Humans</subject><subject>Male</subject><subject>Median Nerve - drug effects</subject><subject>Medical sciences</subject><subject>Neuropharmacology</subject><subject>Nociceptors - drug effects</subject><subject>Pharmacology. Drug treatments</subject><subject>Reaction Time - drug effects</subject><subject>Somatosensory Cortex - drug effects</subject><subject>Transcutaneous Electric Nerve Stimulation</subject><issn>0304-3959</issn><issn>1872-6623</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1984</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFUctu1DAUtRCoTAf-ACQvEIJFwK_E9qYSqlpAqsQG1pZj36huk3iwnam64N_xkNGwg5V1fR7XPgehV5R8oIR2HwknouG61e-UeK8JaUnDnqANVZI1Xcf4U7Q5UZ6j85zvCCGMMX2GzrruYEE36NfVMIArGccBl2Tn7JZiZ4hLxjBWIAVnRzxD2gPOJUzLaEuIM7azxzbvQgozrmO9rXicbIkZ5hzTI4Z9vAePd7HAXIIdM67UOaap-uWlvztsfYGeDRWBl8dzi35cX32__NLcfPv89fLTTeO4lF0DbFBMKNtraCUbJOuFU60X4PpWeSI06frWOsW59x4Y5dINkittnaTQguRb9Hb13aX4c4FczBSyg3Fcv2oUJVow2v2XSLmmiqm2EsVKdCnmnGAwuxQmmx4NJeaQrTlkbw7ZGyXMn3oMq7LXR_-ln8CfRMc-Kv7miNtcgx9qIy7kE01pwqlUf7c_xLFAyvfj8gDJ3IIdy62pNZOO666hWgki6tSsV1t0scqgZr0PVZFdgNmBD6nWYXwM_37-b67EvhA</recordid><startdate>19840401</startdate><enddate>19840401</enddate><creator>Ashton, Heather</creator><creator>Golding, J.F.</creator><creator>Marsh, V.R.</creator><creator>Thompson, J.W.</creator><general>Elsevier B.V</general><general>Lippincott-Raven Publishers.Copyright Lippincott-Raven Publishers</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>19840401</creationdate><title>Effects of transcutaneous electrical nerve stimulation and aspirin on late somatosensory evoked potentials in normal subjects</title><author>Ashton, Heather ; Golding, J.F. ; Marsh, V.R. ; Thompson, J.W.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3776-e2f8248ab9e572f72b4c85d4ecb58d04906b5ac833ddde2137cf7389ac71e5e73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1984</creationdate><topic>Adult</topic><topic>Afferent Pathways - drug effects</topic><topic>Analgesics</topic><topic>Aspirin - pharmacology</topic><topic>Biological and medical sciences</topic><topic>Electric Stimulation</topic><topic>Electric Stimulation Therapy</topic><topic>Evoked Potentials, Somatosensory - drug effects</topic><topic>Humans</topic><topic>Male</topic><topic>Median Nerve - drug effects</topic><topic>Medical sciences</topic><topic>Neuropharmacology</topic><topic>Nociceptors - drug effects</topic><topic>Pharmacology. Drug treatments</topic><topic>Reaction Time - drug effects</topic><topic>Somatosensory Cortex - drug effects</topic><topic>Transcutaneous Electric Nerve Stimulation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ashton, Heather</creatorcontrib><creatorcontrib>Golding, J.F.</creatorcontrib><creatorcontrib>Marsh, V.R.</creatorcontrib><creatorcontrib>Thompson, J.W.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Pain (Amsterdam)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ashton, Heather</au><au>Golding, J.F.</au><au>Marsh, V.R.</au><au>Thompson, J.W.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of transcutaneous electrical nerve stimulation and aspirin on late somatosensory evoked potentials in normal subjects</atitle><jtitle>Pain (Amsterdam)</jtitle><addtitle>Pain</addtitle><date>1984-04-01</date><risdate>1984</risdate><volume>18</volume><issue>4</issue><spage>377</spage><epage>386</epage><pages>377-386</pages><issn>0304-3959</issn><eissn>1872-6623</eissn><coden>PAINDB</coden><abstract>The effects on late somatosensory evoked potentials (SEPs) of transcutaneous nerve stimulation (TENS) and aspirin (600 mg), compared with placebo, were studied in 32 young, healthy male and female volunteers. SEPs were produced by electrical stimulation of the median nerve at moderate, non-painful, intensities. There was a reduction in the peak-to-peak amplitude of the late components N
1P
2 (N
1 latency: 100–160 msec; P
2 latency: 160–260 msec) of the SEP in all groups over time. TENS but not aspirin produced further significant changes compared with placebo, including a fall in N
1P
2 amplitude, an increase in N
1 latency, and a decrease in the total excursion of the SEP between 25 and 450 msec after stimulus onset.</abstract><cop>Amsterdam</cop><pub>Elsevier B.V</pub><pmid>6610161</pmid><doi>10.1016/0304-3959(84)90050-2</doi><tpages>10</tpages></addata></record> |
| fulltext | fulltext |
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| ispartof | Pain (Amsterdam), 1984-04, Vol.18 (4), p.377-386 |
| issn | 0304-3959 1872-6623 |
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| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Adult Afferent Pathways - drug effects Analgesics Aspirin - pharmacology Biological and medical sciences Electric Stimulation Electric Stimulation Therapy Evoked Potentials, Somatosensory - drug effects Humans Male Median Nerve - drug effects Medical sciences Neuropharmacology Nociceptors - drug effects Pharmacology. Drug treatments Reaction Time - drug effects Somatosensory Cortex - drug effects Transcutaneous Electric Nerve Stimulation |
| title | Effects of transcutaneous electrical nerve stimulation and aspirin on late somatosensory evoked potentials in normal subjects |
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