B lymphocyte precursors in embryonic and adult W anemic mice

Mice homozygous for mutations at the dominant spotting or W locus on chromosome 5 have been extensively used as models of severe macrocytic anemia caused by defective hemopoietic stem cells. We examined cells of the developing B lineage in adult and embryonic W anemic mice both by phenotypic analyse...

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Veröffentlicht in:	The Journal of immunology (1950) 1984-06, Vol.132 (6), p.2724-2729
Hauptverfasser:	Landreth, KS, Kincade, PW, Lee, G, Harrison, DE
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Anemia, Macrocytic - blood Anemia, Macrocytic - immunology Anemia, Macrocytic - physiopathology Anemias. Hemoglobinopathies Animals B-Lymphocytes - immunology B-Lymphocytes - pathology Biological and medical sciences Bone Marrow - pathology Cell Count Cell Differentiation Diseases of red blood cells Embryo, Mammalian - cytology Embryo, Mammalian - immunology Female Hematologic and hematopoietic diseases Hematopoietic Stem Cells - immunology Hematopoietic Stem Cells - pathology Liver - cytology Lymphocyte Activation Medical sciences Mice Mice, Inbred CBA Mice, Mutant Strains Pregnancy Spleen - pathology
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