Kinetics of Neutral Amino Acid Transport Across the Blood‐Brain Barrier

: Neutral amino acid (NAA) transport across the blood‐brain barrier was examined in pentobarbital‐anesthetized rats with an in situ brain perfusion technique. Fourteen of 16 plasma NAAs showed measurable affinity for the cerebrovascular NAA transport system. Values of the transport constants (Vmax,...

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Veröffentlicht in:	Journal of neurochemistry 1987-11, Vol.49 (5), p.1651-1658
Hauptverfasser:	Smith, Quentin R., Momma, Seiji, Aoyagi, Masaki, Rapoport, Stanley I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acid amino acids Amino Acids - blood Amino Acids - metabolism Animals Binding, Competitive Biological Transport Blood-Brain Barrier Brain Brain - blood supply Brain - metabolism Capillary Capillary Permeability Cerebral Cortex - metabolism Kinetics Male Perfusion Perme‐ability Phenylalanine - metabolism Rats Transport
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