Heterogeneity in the production of collagens and fibronectin by morphologically distinct clones of a human tumor cell line: evidence for intratumoral diversity in matrix protein biosynthesis

Recent studies of murine tumor models and certain human tumor cell lines have provided evidence for intratumor heterogeneity in expression of extracellular matrix receptors and in the elaboration of matrix-degrading enzymes. However, little is known about possible intratumoral heterogeneity in the p...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1987-11, Vol.47 (22), p.6086-6092
Hauptverfasser:	CROUCH, E. C, STONE, K. R, BLOCH, M, MCDIVITT, R. W
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Carcinoma, Small Cell - pathology Cell Line Clone Cells Collagen - biosynthesis Collagen - isolation & purification Extracellular Matrix - metabolism Fibronectins - biosynthesis Fibronectins - isolation & purification General aspects (metabolism, cell proliferation, established cell line...) Humans Lung Neoplasms - pathology Medical sciences Tumor cell Tumors
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