Detergent induced lysis of erythrocytes in kwashiorkor

The effect of the non-ionic detergent Nonidet P40 on lysis of erythrocytes in children suffering from kwashiorkor was studied. The concentration of the detergent causing 50% haemolysis was significantly reduced in these patients. Detergent haemolysis was more sensitive than osmotic fragility (which...

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Veröffentlicht in:Clinica chimica acta 1987-09, Vol.168 (1), p.1-5
Hauptverfasser: Rao, Aravinda, Onuora, Christiana U., Cherian, Annie
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container_title Clinica chimica acta
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creator Rao, Aravinda
Onuora, Christiana U.
Cherian, Annie
description The effect of the non-ionic detergent Nonidet P40 on lysis of erythrocytes in children suffering from kwashiorkor was studied. The concentration of the detergent causing 50% haemolysis was significantly reduced in these patients. Detergent haemolysis was more sensitive than osmotic fragility (which was reduced). The abnormality was only slight in marasmic children.
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source Elsevier ScienceDirect Journals Complete - AutoHoldings; MEDLINE
subjects Anemia - blood
Applied sciences
Child
Detergent induced hemolysis
Detergents - pharmacology
Erythrocyte membrane
Exact sciences and technology
Hemolysis - drug effects
Humans
Hypotonic Solutions
Kwashiorkor
Kwashiorkor - blood
Kwashiorkor - diagnosis
Osmotic fragility
Other techniques and industries
Polyethylene Glycols - pharmacology
Surface-Active Agents - pharmacology
title Detergent induced lysis of erythrocytes in kwashiorkor
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