Effect of Preheating on the Permeability of Neonatal Rat Stratum Corneum to Alkanols

We heated flat sheets of neonatal rat stratum corneum for various times at temperatures between 40 and 90°C before determining the permeability coefficient (Kp) of propanol and/or hexanol from water. Below 70°C, Kp remained constant; at 75°C, Kp increased linearly with exposure time; at 80°C and abo...

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Veröffentlicht in:	Journal of investigative dermatology 1987-10, Vol.89 (4), p.430-433
Hauptverfasser:	Al-Saidan, Saleh M.A., Winfield, Arthur J., Selkirk, Alasdair B.
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Propanol - metabolism Animals Biological and medical sciences Dimethyl Sulfoxide - pharmacology Epidermis - physiology Gases Hexanols - metabolism Hot Temperature In Vitro Techniques Lipids - physiology Medical sciences Permeability Pharmacology. Drug treatments Rats Skin, nail, hair, dermoskeleton Time Factors
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