Release Characteristics of Nifedipine Sustained-Release Granules in Vitro and in Healthy Subjects

The release characteristics of nifedipine sustained-release granules, composed of ethylcellulose, hydroxypropylmethylcellulose and corn starch, were examined in vitro as well as in healthy subjects. The release of nifedipine from the granules in vitro was not first-order, but a linear relationship u...

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