The effects of aluminum chloride on the rate of secretion of the cerebrospinal fluid

The claim that AlCl 3 could produce 100% inhibition of cerebrospinal fluid secretion was investigated using ventriculocisternal perfusion in the rabbit, and it was shown that a large part of this inhibition was an artefact due to a pH sensitivity of Blue Dextran, used as an indiffusible marker, caus...

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Veröffentlicht in:	Exp. Neurol.; (United States) 1987-11, Vol.98 (2), p.436-452
Hauptverfasser:	Zlokovic, B.V., Davson, H., Preston, J.E., Segal, M.B.
Format:	Artikel
Sprache:	eng
Schlagworte:	560300 - Chemicals Metabolism & Toxicology Acetazolamide - pharmacology ALKALI METAL ISOTOPES ALUMINIUM CHLORIDES ALUMINIUM COMPOUNDS Aluminum - pharmacology Aluminum Chloride Aluminum Compounds ANIMALS BETA DECAY RADIOISOTOPES BETA-PLUS DECAY RADIOISOTOPES Biological and medical sciences BIOLOGICAL EFFECTS BIOLOGICAL MATERIALS BLOOD PRESSURE BODY BODY FLUIDS BRAIN Brain - metabolism BUFFERS CENTRAL NERVOUS SYSTEM Cerebral circulation. Blood-brain barrier. Choroid plexus. Cerebrospinal fluid. Circumventricular organ. Meninges CEREBROSPINAL FLUID Cerebrospinal Fluid - metabolism CHLORIDES Chlorides - pharmacology CHLORINE COMPOUNDS Dextrans Female Fundamental and applied biological sciences. Psychology HALIDES HALOGEN COMPOUNDS Hydrogen-Ion Concentration INHIBITION ISOTOPE APPLICATIONS ISOTOPES LABELLED COMPOUNDS LIGHT NUCLEI Male MAMMALS MATERIALS NERVOUS SYSTEM NUCLEI ODD-ODD NUCLEI ORGANS Osmolar Concentration PERFUSED ORGANS Perfusion RABBITS RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT RADIOISOTOPES SECRETION Sodium - blood Sodium - metabolism SODIUM 22 SODIUM ISOTOPES Sodium Radioisotopes TRACER TECHNIQUES Tritium TRITIUM COMPOUNDS VERTEBRATES Vertebrates: nervous system and sense organs YEARS LIVING RADIOISOTOPES
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