Measurements of hCG and PAPP-A in uncommon types of ectopic gestation
Seven out of 54 women with ectopic gestation had uncommon features such as extra-tubal implantation or multiple intratubal pregnancy. Depressed levels (< 10th centile) or apparent absence of circulating human chorionic gonadotrophin (hCG) and pregnancy-associated plasma protein A (PAPP-A) were se...
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| Veröffentlicht in: | European journal of obstetrics & gynecology and reproductive biology 1987-09, Vol.26 (1), p.33-37 |
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| container_title | European journal of obstetrics & gynecology and reproductive biology |
| container_volume | 26 |
| creator | Poulsen, Henning K. Westergaard, Jes G. Teisner, Børge Bolton, Anthony E. Norman, Robert G. Grudzinskas, Jurgis G. |
| description | Seven out of 54 women with ectopic gestation had uncommon features such as extra-tubal implantation or multiple intratubal pregnancy. Depressed levels (< 10th centile) or apparent absence of circulating human chorionic gonadotrophin (hCG) and pregnancy-associated plasma protein A (PAPP-A) were seen respectively in 5 and 7 of 7 women studied. Normal levels of hCG were seen in two women, one with an abdominal and one with an angular pregnancy. These data suggest that the synthesis of placental proteins in ectopic pregnancies is independent of the site of implantation and the number of embryos. Measurements of maternal levels of the 2 placental proteins seem to be applicable as auxiliary diagnostic tests for ectopic pregnancy, regardless of the site of implantation. |
| doi_str_mv | 10.1016/0028-2243(87)90007-4 |
| format | Article |
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Depressed levels (< 10th centile) or apparent absence of circulating human chorionic gonadotrophin (hCG) and pregnancy-associated plasma protein A (PAPP-A) were seen respectively in 5 and 7 of 7 women studied. Normal levels of hCG were seen in two women, one with an abdominal and one with an angular pregnancy. These data suggest that the synthesis of placental proteins in ectopic pregnancies is independent of the site of implantation and the number of embryos. 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Depressed levels (< 10th centile) or apparent absence of circulating human chorionic gonadotrophin (hCG) and pregnancy-associated plasma protein A (PAPP-A) were seen respectively in 5 and 7 of 7 women studied. Normal levels of hCG were seen in two women, one with an abdominal and one with an angular pregnancy. These data suggest that the synthesis of placental proteins in ectopic pregnancies is independent of the site of implantation and the number of embryos. Measurements of maternal levels of the 2 placental proteins seem to be applicable as auxiliary diagnostic tests for ectopic pregnancy, regardless of the site of implantation.</description><subject>Biological and medical sciences</subject><subject>Chorionic Gonadotropin - blood</subject><subject>Diseases of mother, fetus and pregnancy</subject><subject>Ectopic gestation</subject><subject>Female</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>hCG</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>PAPP-A</subject><subject>Pregnancy</subject><subject>Pregnancy Proteins - metabolism</subject><subject>Pregnancy, Ectopic - blood</subject><subject>Pregnancy, Multiple</subject><subject>Pregnancy-Associated Plasma Protein-A - metabolism</subject><subject>Pregnancy. Fetus. 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| fulltext | fulltext |
| identifier | ISSN: 0301-2115 |
| ispartof | European journal of obstetrics & gynecology and reproductive biology, 1987-09, Vol.26 (1), p.33-37 |
| issn | 0301-2115 1872-7654 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Biological and medical sciences Chorionic Gonadotropin - blood Diseases of mother, fetus and pregnancy Ectopic gestation Female Gynecology. Andrology. Obstetrics hCG Humans Medical sciences PAPP-A Pregnancy Pregnancy Proteins - metabolism Pregnancy, Ectopic - blood Pregnancy, Multiple Pregnancy-Associated Plasma Protein-A - metabolism Pregnancy. Fetus. Placenta Unusual site of implantation |
| title | Measurements of hCG and PAPP-A in uncommon types of ectopic gestation |
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