Hormonal changes in normal men under marginally negative energy balance
Six men were confined to a metabolic unit for 105 days. Their assigned work and energy intake were varied throughout six metabolic periods in order to create either a marginally negative (−15%) or an equilibrated energy balance. They were fed a defined diet providing a constant amount of protein. At...
Gespeichert in:
| Veröffentlicht in: | The American journal of clinical nutrition 1984-06, Vol.39 (6), p.930-936 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 936 |
|---|---|
| container_issue | 6 |
| container_start_page | 930 |
| container_title | The American journal of clinical nutrition |
| container_volume | 39 |
| creator | Garrel, D R Todd, K S Pugeat, M M Calloway, D H |
| description | Six men were confined to a metabolic unit for 105 days. Their assigned work and energy intake were varied throughout six metabolic periods in order to create either a marginally negative (−15%) or an equilibrated energy balance. They were fed a defined diet providing a constant amount of protein. At each metabolic period, T4, T3, reverse T3(rT3), free T3, free reverse T3, thyroid-stimulating hormone, cortisol, cortisol-binding globulin, testosterone, and testosterone/estradiol-binding globulin were measured. Free urinary cortisol was measured daily. Results show that serum thyroid hormones are sensitive to marginal changes in energy intake, expenditure, and balance. The ratio T4/T3 appears to be more sensitive to the balance itself, with the ratio T3/rT3 being more sensitive to the intake and expenditure level at which this balance is established. Regulations of T3 and rT3 production are probably distinct. Urinary cortisol did not show any variation that could be related to the energy balance. However, daily urinary cortisol was correlated to daily urinary nitrogen excretion. No change in serum testosterone was found. |
| doi_str_mv | 10.1093/ajcn/39.6.930 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_81050213</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0002916523247024</els_id><sourcerecordid>81050213</sourcerecordid><originalsourceid>FETCH-LOGICAL-c442t-aa52fb3efd5a469b1be140c8538d4398923771ecd9dadaa1aa3b12c097dbe4123</originalsourceid><addsrcrecordid>eNp1kElLBDEQRoMoOi5HL4LQB_HWY5becpTBDQQP6jlUJ9VtpDutyYww_94aZvDmJYH6Hh9Vj7FzweeCa3UDnzbcKD2v5lrxPTYTWjW5krzeZzPOucy1qMojdpzSJ-dCFk11yA6rUmleFTP28DjFcQowZPYDQo8p8yELNKPJiCFbBYcxGyH2nqBhnQXsYel_MMOAsV9nLQwQLJ6ygw6GhGe7_4S939-9LR7z55eHp8Xtc26LQi5zgFJ2rcLOlVBUuhUtioLbplSNK5RutFR1LdA67cABCADVCmm5rl2LhZDqhF1ve7_i9L3CtDSjTxYHWgKnVTKN4CWXQhGYb0Ebp5QiduYrerpjbQQ3G3FmI84obSpD4oi_3BWv2hHdH70zRfnVLodkYegiXe3TH6Y3lWJTc7HFOpgM9JGQ91c6jyt6_gkpk5rCehsi6fvxGE2yHkmt8xHt0rjJ_7P6L5-Omfk</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>81050213</pqid></control><display><type>article</type><title>Hormonal changes in normal men under marginally negative energy balance</title><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>Garrel, D R ; Todd, K S ; Pugeat, M M ; Calloway, D H</creator><creatorcontrib>Garrel, D R ; Todd, K S ; Pugeat, M M ; Calloway, D H</creatorcontrib><description>Six men were confined to a metabolic unit for 105 days. Their assigned work and energy intake were varied throughout six metabolic periods in order to create either a marginally negative (−15%) or an equilibrated energy balance. They were fed a defined diet providing a constant amount of protein. At each metabolic period, T4, T3, reverse T3(rT3), free T3, free reverse T3, thyroid-stimulating hormone, cortisol, cortisol-binding globulin, testosterone, and testosterone/estradiol-binding globulin were measured. Free urinary cortisol was measured daily. Results show that serum thyroid hormones are sensitive to marginal changes in energy intake, expenditure, and balance. The ratio T4/T3 appears to be more sensitive to the balance itself, with the ratio T3/rT3 being more sensitive to the intake and expenditure level at which this balance is established. Regulations of T3 and rT3 production are probably distinct. Urinary cortisol did not show any variation that could be related to the energy balance. However, daily urinary cortisol was correlated to daily urinary nitrogen excretion. No change in serum testosterone was found.</description><identifier>ISSN: 0002-9165</identifier><identifier>EISSN: 1938-3207</identifier><identifier>DOI: 10.1093/ajcn/39.6.930</identifier><identifier>PMID: 6539064</identifier><identifier>CODEN: AJCNAC</identifier><language>eng</language><publisher>Bethesda, MD: Elsevier Inc</publisher><subject>Adult ; Biological and medical sciences ; Carrier Proteins - metabolism ; cortisol ; Diet ; energy deficit ; Energy Metabolism ; Fasting ; Fundamental and applied biological sciences. Psychology ; Hormone ; Humans ; Hydrocortisone - blood ; Hydrocortisone - metabolism ; Hydrocortisone - urine ; Intermediate and energetic metabolism ; Male ; Metabolisms and neurohumoral controls ; nitrogen ; Nitrogen - urine ; Sex Hormone-Binding Globulin - metabolism ; Testosterone - blood ; thyroid ; Thyroid Hormones - blood ; Thyrotropin - blood ; Vertebrates: anatomy and physiology, studies on body, several organs or systems</subject><ispartof>The American journal of clinical nutrition, 1984-06, Vol.39 (6), p.930-936</ispartof><rights>1984 American Society for Nutrition.</rights><rights>1985 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c442t-aa52fb3efd5a469b1be140c8538d4398923771ecd9dadaa1aa3b12c097dbe4123</citedby><cites>FETCH-LOGICAL-c442t-aa52fb3efd5a469b1be140c8538d4398923771ecd9dadaa1aa3b12c097dbe4123</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=9109310$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6539064$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Garrel, D R</creatorcontrib><creatorcontrib>Todd, K S</creatorcontrib><creatorcontrib>Pugeat, M M</creatorcontrib><creatorcontrib>Calloway, D H</creatorcontrib><title>Hormonal changes in normal men under marginally negative energy balance</title><title>The American journal of clinical nutrition</title><addtitle>Am J Clin Nutr</addtitle><description>Six men were confined to a metabolic unit for 105 days. Their assigned work and energy intake were varied throughout six metabolic periods in order to create either a marginally negative (−15%) or an equilibrated energy balance. They were fed a defined diet providing a constant amount of protein. At each metabolic period, T4, T3, reverse T3(rT3), free T3, free reverse T3, thyroid-stimulating hormone, cortisol, cortisol-binding globulin, testosterone, and testosterone/estradiol-binding globulin were measured. Free urinary cortisol was measured daily. Results show that serum thyroid hormones are sensitive to marginal changes in energy intake, expenditure, and balance. The ratio T4/T3 appears to be more sensitive to the balance itself, with the ratio T3/rT3 being more sensitive to the intake and expenditure level at which this balance is established. Regulations of T3 and rT3 production are probably distinct. Urinary cortisol did not show any variation that could be related to the energy balance. However, daily urinary cortisol was correlated to daily urinary nitrogen excretion. No change in serum testosterone was found.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Carrier Proteins - metabolism</subject><subject>cortisol</subject><subject>Diet</subject><subject>energy deficit</subject><subject>Energy Metabolism</subject><subject>Fasting</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Hormone</subject><subject>Humans</subject><subject>Hydrocortisone - blood</subject><subject>Hydrocortisone - metabolism</subject><subject>Hydrocortisone - urine</subject><subject>Intermediate and energetic metabolism</subject><subject>Male</subject><subject>Metabolisms and neurohumoral controls</subject><subject>nitrogen</subject><subject>Nitrogen - urine</subject><subject>Sex Hormone-Binding Globulin - metabolism</subject><subject>Testosterone - blood</subject><subject>thyroid</subject><subject>Thyroid Hormones - blood</subject><subject>Thyrotropin - blood</subject><subject>Vertebrates: anatomy and physiology, studies on body, several organs or systems</subject><issn>0002-9165</issn><issn>1938-3207</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1984</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kElLBDEQRoMoOi5HL4LQB_HWY5becpTBDQQP6jlUJ9VtpDutyYww_94aZvDmJYH6Hh9Vj7FzweeCa3UDnzbcKD2v5lrxPTYTWjW5krzeZzPOucy1qMojdpzSJ-dCFk11yA6rUmleFTP28DjFcQowZPYDQo8p8yELNKPJiCFbBYcxGyH2nqBhnQXsYel_MMOAsV9nLQwQLJ6ygw6GhGe7_4S939-9LR7z55eHp8Xtc26LQi5zgFJ2rcLOlVBUuhUtioLbplSNK5RutFR1LdA67cABCADVCmm5rl2LhZDqhF1ve7_i9L3CtDSjTxYHWgKnVTKN4CWXQhGYb0Ebp5QiduYrerpjbQQ3G3FmI84obSpD4oi_3BWv2hHdH70zRfnVLodkYegiXe3TH6Y3lWJTc7HFOpgM9JGQ91c6jyt6_gkpk5rCehsi6fvxGE2yHkmt8xHt0rjJ_7P6L5-Omfk</recordid><startdate>198406</startdate><enddate>198406</enddate><creator>Garrel, D R</creator><creator>Todd, K S</creator><creator>Pugeat, M M</creator><creator>Calloway, D H</creator><general>Elsevier Inc</general><general>American Society for Clinical Nutrition</general><scope>6I.</scope><scope>AAFTH</scope><scope>FBQ</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198406</creationdate><title>Hormonal changes in normal men under marginally negative energy balance</title><author>Garrel, D R ; Todd, K S ; Pugeat, M M ; Calloway, D H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c442t-aa52fb3efd5a469b1be140c8538d4398923771ecd9dadaa1aa3b12c097dbe4123</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1984</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Carrier Proteins - metabolism</topic><topic>cortisol</topic><topic>Diet</topic><topic>energy deficit</topic><topic>Energy Metabolism</topic><topic>Fasting</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Hormone</topic><topic>Humans</topic><topic>Hydrocortisone - blood</topic><topic>Hydrocortisone - metabolism</topic><topic>Hydrocortisone - urine</topic><topic>Intermediate and energetic metabolism</topic><topic>Male</topic><topic>Metabolisms and neurohumoral controls</topic><topic>nitrogen</topic><topic>Nitrogen - urine</topic><topic>Sex Hormone-Binding Globulin - metabolism</topic><topic>Testosterone - blood</topic><topic>thyroid</topic><topic>Thyroid Hormones - blood</topic><topic>Thyrotropin - blood</topic><topic>Vertebrates: anatomy and physiology, studies on body, several organs or systems</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Garrel, D R</creatorcontrib><creatorcontrib>Todd, K S</creatorcontrib><creatorcontrib>Pugeat, M M</creatorcontrib><creatorcontrib>Calloway, D H</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>AGRIS</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of clinical nutrition</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Garrel, D R</au><au>Todd, K S</au><au>Pugeat, M M</au><au>Calloway, D H</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hormonal changes in normal men under marginally negative energy balance</atitle><jtitle>The American journal of clinical nutrition</jtitle><addtitle>Am J Clin Nutr</addtitle><date>1984-06</date><risdate>1984</risdate><volume>39</volume><issue>6</issue><spage>930</spage><epage>936</epage><pages>930-936</pages><issn>0002-9165</issn><eissn>1938-3207</eissn><coden>AJCNAC</coden><abstract>Six men were confined to a metabolic unit for 105 days. Their assigned work and energy intake were varied throughout six metabolic periods in order to create either a marginally negative (−15%) or an equilibrated energy balance. They were fed a defined diet providing a constant amount of protein. At each metabolic period, T4, T3, reverse T3(rT3), free T3, free reverse T3, thyroid-stimulating hormone, cortisol, cortisol-binding globulin, testosterone, and testosterone/estradiol-binding globulin were measured. Free urinary cortisol was measured daily. Results show that serum thyroid hormones are sensitive to marginal changes in energy intake, expenditure, and balance. The ratio T4/T3 appears to be more sensitive to the balance itself, with the ratio T3/rT3 being more sensitive to the intake and expenditure level at which this balance is established. Regulations of T3 and rT3 production are probably distinct. Urinary cortisol did not show any variation that could be related to the energy balance. However, daily urinary cortisol was correlated to daily urinary nitrogen excretion. No change in serum testosterone was found.</abstract><cop>Bethesda, MD</cop><pub>Elsevier Inc</pub><pmid>6539064</pmid><doi>10.1093/ajcn/39.6.930</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0002-9165 |
| ispartof | The American journal of clinical nutrition, 1984-06, Vol.39 (6), p.930-936 |
| issn | 0002-9165 1938-3207 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_81050213 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Adult Biological and medical sciences Carrier Proteins - metabolism cortisol Diet energy deficit Energy Metabolism Fasting Fundamental and applied biological sciences. Psychology Hormone Humans Hydrocortisone - blood Hydrocortisone - metabolism Hydrocortisone - urine Intermediate and energetic metabolism Male Metabolisms and neurohumoral controls nitrogen Nitrogen - urine Sex Hormone-Binding Globulin - metabolism Testosterone - blood thyroid Thyroid Hormones - blood Thyrotropin - blood Vertebrates: anatomy and physiology, studies on body, several organs or systems |
| title | Hormonal changes in normal men under marginally negative energy balance |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-28T16%3A52%3A08IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Hormonal%20changes%20in%20normal%20men%20under%20marginally%20negative%20energy%20balance&rft.jtitle=The%20American%20journal%20of%20clinical%20nutrition&rft.au=Garrel,%20D%20R&rft.date=1984-06&rft.volume=39&rft.issue=6&rft.spage=930&rft.epage=936&rft.pages=930-936&rft.issn=0002-9165&rft.eissn=1938-3207&rft.coden=AJCNAC&rft_id=info:doi/10.1093/ajcn/39.6.930&rft_dat=%3Cproquest_cross%3E81050213%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=81050213&rft_id=info:pmid/6539064&rft_els_id=S0002916523247024&rfr_iscdi=true |