The concentrations of urinary prostaglandins E and plasma prostaglandins F2α and E during induction of ovulation with human gonadotropins
Plasma prostaglandins F2 alpha and E (PGF2 alpha, PGE) and urinary PGE were measured in 10 women treated with human gonadotropins (HMG) and subsequently with human chorionic gonadotropins (HCG). Five women became pregnant (6 pregnancies). There was no correlation between concentrations of plasma PGF...
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| Veröffentlicht in: | Prostaglandins leukotrienes and medicine 1984-02, Vol.13 (2), p.197-209 |
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| container_title | Prostaglandins leukotrienes and medicine |
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| creator | MOUTQUIN, J. M WYMAN, H VAN CAMPENHOUT, J LORD, J |
| description | Plasma prostaglandins F2 alpha and E (PGF2 alpha, PGE) and urinary PGE were measured in 10 women treated with human gonadotropins (HMG) and subsequently with human chorionic gonadotropins (HCG). Five women became pregnant (6 pregnancies). There was no correlation between concentrations of plasma PGF2 alpha or PGE and plasma estradiol or progesterone. Urinary PGE concentrations showed a positive correlation with estradiol before HCG and a negative correlation with progesterone after HCG, only in women who subsequently became pregnant. Higher urinary PGE concentrations before HCG suggest that either HMG or rising estradiol levels stimulate PGE renal production. The significant negative correlation between urinary PGE and progesterone concentrations, after HCG, in those patients who became pregnant suggests that ovarian production of progesterone may decrease renal production of PGE. |
| doi_str_mv | 10.1016/0262-1746(84)90010-6 |
| format | Article |
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The significant negative correlation between urinary PGE and progesterone concentrations, after HCG, in those patients who became pregnant suggests that ovarian production of progesterone may decrease renal production of PGE.</description><identifier>ISSN: 0262-1746</identifier><identifier>DOI: 10.1016/0262-1746(84)90010-6</identifier><identifier>PMID: 6585841</identifier><language>eng</language><publisher>Edinburgh: Churchill Livingstone</publisher><subject>Biological and medical sciences ; Birth control ; Dinoprost ; Estradiol - blood ; Female ; Gonadotropins - pharmacology ; Gynecology. Andrology. Obstetrics ; Humans ; Medical sciences ; Ovulation - drug effects ; Progesterone - blood ; Prostaglandins E - blood ; Prostaglandins E - metabolism ; Prostaglandins E - urine ; Prostaglandins F - blood ; Sterility. 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Higher urinary PGE concentrations before HCG suggest that either HMG or rising estradiol levels stimulate PGE renal production. The significant negative correlation between urinary PGE and progesterone concentrations, after HCG, in those patients who became pregnant suggests that ovarian production of progesterone may decrease renal production of PGE.</description><subject>Biological and medical sciences</subject><subject>Birth control</subject><subject>Dinoprost</subject><subject>Estradiol - blood</subject><subject>Female</subject><subject>Gonadotropins - pharmacology</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Ovulation - drug effects</subject><subject>Progesterone - blood</subject><subject>Prostaglandins E - blood</subject><subject>Prostaglandins E - metabolism</subject><subject>Prostaglandins E - urine</subject><subject>Prostaglandins F - blood</subject><subject>Sterility. 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Urinary PGE concentrations showed a positive correlation with estradiol before HCG and a negative correlation with progesterone after HCG, only in women who subsequently became pregnant. Higher urinary PGE concentrations before HCG suggest that either HMG or rising estradiol levels stimulate PGE renal production. The significant negative correlation between urinary PGE and progesterone concentrations, after HCG, in those patients who became pregnant suggests that ovarian production of progesterone may decrease renal production of PGE.</abstract><cop>Edinburgh</cop><cop>New York, NY</cop><pub>Churchill Livingstone</pub><pmid>6585841</pmid><doi>10.1016/0262-1746(84)90010-6</doi><tpages>13</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0262-1746 |
| ispartof | Prostaglandins leukotrienes and medicine, 1984-02, Vol.13 (2), p.197-209 |
| issn | 0262-1746 |
| language | eng |
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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Biological and medical sciences Birth control Dinoprost Estradiol - blood Female Gonadotropins - pharmacology Gynecology. Andrology. Obstetrics Humans Medical sciences Ovulation - drug effects Progesterone - blood Prostaglandins E - blood Prostaglandins E - metabolism Prostaglandins E - urine Prostaglandins F - blood Sterility. Assisted procreation |
| title | The concentrations of urinary prostaglandins E and plasma prostaglandins F2α and E during induction of ovulation with human gonadotropins |
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