Effects of alismol isolated from Alismatis Rhizoma on calcium-induced contraction in the rabbit thoracic aorta

We examined the inhibitory effects of alismol, a sesquiterpenoid isolated from Alismatis Rhizoma, on vascular contractions induced by high concentrations of K + and Ca 2+, and on 4 5Ca 2+ retention in normal and in high K +-containing medium. Alismol affected neither the resting tension nor the 4 5C...

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Veröffentlicht in:	Life Sci.; (United States) 1987-10, Vol.41 (15), p.1845-1852
Hauptverfasser:	Matsuda, Hisashi, Kobayashi, Goro, Yamahara, Johji, Fujimura, Hajime, Kurahashi, Kazuyoshi, Fujiwara, Motohatsu
Format:	Artikel
Sprache:	eng
Schlagworte:	550201 - Biochemistry- Tracer Techniques ALKALI METAL COMPOUNDS ALKALINE EARTH ISOTOPES ALKALINE EARTH METAL COMPOUNDS ANIMALS AORTA Aorta, Thoracic - drug effects Aorta, Thoracic - physiology ARTERIES BASIC BIOLOGICAL SCIENCES BETA DECAY RADIOISOTOPES BETA-MINUS DECAY RADIOISOTOPES Biological and medical sciences BIOLOGICAL EFFECTS BLOOD VESSELS BODY Calcium - metabolism Calcium - pharmacology CALCIUM 45 CALCIUM COMPOUNDS CALCIUM ISOTOPES CARDIOVASCULAR SYSTEM CATIONS CHARGED PARTICLES CONTRACTION DATA DAYS LIVING RADIOISOTOPES DRUGS EVEN-ODD NUCLEI EXPERIMENTAL DATA General pharmacology In Vitro Techniques INFORMATION INHIBITION INTERMEDIATE MASS NUCLEI IONS ISOTOPE APPLICATIONS ISOTOPES Male MAMMALS Medical sciences MEMBRANE TRANSPORT Muscle Contraction - drug effects Muscle, Smooth, Vascular - drug effects Muscle, Smooth, Vascular - physiology Norepinephrine - pharmacology NUCLEI NUMERICAL DATA ORGANS Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Potassium - pharmacology POTASSIUM COMPOUNDS RABBITS RADIOISOTOPES Sesquiterpenes - pharmacology TRACER TECHNIQUES VERTEBRATES
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