A correlation between aging and DNA repair in human epidermal cells

Ultraviolet-induced unscheduled DNA synthesis ( i.e. repair synthesis) in human epidermal cells was measured as a function of age. Normal mammary skin specimens were obtained at surgery from 36 female patients, ranging in age from 17 to 77 years. The enzymatically isolated epidermal cells were analy...

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Veröffentlicht in:	Mechanisms of ageing and development 1984-01, Vol.24 (3), p.283-292
Hauptverfasser:	Gerda Nette, E., Xi, Yu-Ping, Sun, Yu-Kay, Andrews, Alan D., King, Donald W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Ageing, cell death Aging Autoradiography Biological and medical sciences Cell physiology DNA - biosynthesis DNA Repair - radiation effects DNA repair synthesis Female Fundamental and applied biological sciences. Psychology Human epithelial (epidermal) cells Humans Middle Aged Molecular and cellular biology Skin - cytology Skin - metabolism Skin - radiation effects Ultraviolet Rays - adverse effects UV irradiation
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