Noradrenaline-induced emesis: Alpha-2 adrenoceptor mediation in the area postrema

The emetic action of noradrenaline was investigated in unanaesthetized cats, after it was injected into the cerebral ventricles through chronically implanted cannulae. Intracerebroventricular injection of noradrenaline produced dose-dependent and shortlasting emesis, which was abolished after ablati...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Neuropharmacology 1987-08, Vol.26 (8), p.1157-1165
Hauptverfasser:	Beleslin, D.B., Štrbac, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	5,6-Dihydroxytryptamine - pharmacology Adrenergic alpha-Antagonists - pharmacology Adrenergic beta-Antagonists - pharmacology alpha-2 postsynaptic adrenoceptors alpha-Methyltyrosine Animals area postrema Atropine - pharmacology Biological and medical sciences Bretylium Compounds - pharmacology Cats Cerebral Ventricles - drug effects Cerebral Ventricles - metabolism Copper - pharmacology Copper Sulfate Digestive system emesis emetic region of the brainstem reticular formation Ethylenediamines - pharmacology Female Hemicholinium 3 - pharmacology Injections, Intraventricular Male Mecamylamine - pharmacology Medical sciences Methyltyrosines - pharmacology Methysergide - pharmacology noradrenaline Norepinephrine - administration & dosage Norepinephrine - pharmacology Pharmacology. Drug treatments Receptors, Adrenergic, alpha - metabolism Reserpine - pharmacology Vomiting - chemically induced
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!