Serial passage of tumors in mice in the study of tumor progression and testing of antineoplastic drugs

AKR lymphoma cells derived from spontaneous tumors were serially transplanted at identical inocula. The degree of malignancy and sensitivity to the polysaccharide levan and methotrexate were tested at each transfer by assessing the lag of development of primary and distant tumors and survival of mic...

Ausführliche Beschreibung