Disseminated aspergillosis presenting with endophthalmitis: A case report and a review of the literature
A patient with idiopathic thrombocytosis developed sudden loss of vision in his left eye secondary to endophthalmitis caused by Aspergillus flavus. He subsequently manifested other symptoms and signs of disseminated infection, and eventually died despite prompt initiation of appropriate parenteral a...
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| Veröffentlicht in: | Cancer 1984-05, Vol.53 (9), p.1995-2001 |
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| container_end_page | 2001 |
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| container_issue | 9 |
| container_start_page | 1995 |
| container_title | Cancer |
| container_volume | 53 |
| creator | Demicco, Deborah D. Reichman, Richard C. Violette, E. Jeffrey Winn, Washington C. |
| description | A patient with idiopathic thrombocytosis developed sudden loss of vision in his left eye secondary to endophthalmitis caused by Aspergillus flavus. He subsequently manifested other symptoms and signs of disseminated infection, and eventually died despite prompt initiation of appropriate parenteral antifungal therapy. A period of profound, iatrogenic neutropenia preceded the development of his terminal infection. Previously reported cases of hematogenously acquired Aspergillus endophthalmitis are reviewed, and approaches to diagnosis and management are discussed. The frequency of eye involvement in cases of disseminated aspergillosis is unknown, but it may be greater than appreciated previously. |
| doi_str_mv | 10.1002/1097-0142(19840501)53:9<1995::AID-CNCR2820530932>3.0.CO;2-S |
| format | Article |
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Jeffrey ; Winn, Washington C.</creator><creatorcontrib>Demicco, Deborah D. ; Reichman, Richard C. ; Violette, E. Jeffrey ; Winn, Washington C.</creatorcontrib><description>A patient with idiopathic thrombocytosis developed sudden loss of vision in his left eye secondary to endophthalmitis caused by Aspergillus flavus. He subsequently manifested other symptoms and signs of disseminated infection, and eventually died despite prompt initiation of appropriate parenteral antifungal therapy. A period of profound, iatrogenic neutropenia preceded the development of his terminal infection. Previously reported cases of hematogenously acquired Aspergillus endophthalmitis are reviewed, and approaches to diagnosis and management are discussed. 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Jeffrey</creatorcontrib><creatorcontrib>Winn, Washington C.</creatorcontrib><title>Disseminated aspergillosis presenting with endophthalmitis: A case report and a review of the literature</title><title>Cancer</title><addtitle>Cancer</addtitle><description>A patient with idiopathic thrombocytosis developed sudden loss of vision in his left eye secondary to endophthalmitis caused by Aspergillus flavus. He subsequently manifested other symptoms and signs of disseminated infection, and eventually died despite prompt initiation of appropriate parenteral antifungal therapy. A period of profound, iatrogenic neutropenia preceded the development of his terminal infection. Previously reported cases of hematogenously acquired Aspergillus endophthalmitis are reviewed, and approaches to diagnosis and management are discussed. The frequency of eye involvement in cases of disseminated aspergillosis is unknown, but it may be greater than appreciated previously.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aspergillosis - diagnosis</subject><subject>Aspergillus flavus - growth & development</subject><subject>Biological and medical sciences</subject><subject>Brain Abscess - diagnostic imaging</subject><subject>Brain Abscess - etiology</subject><subject>Child</subject><subject>Endophthalmitis - diagnosis</subject><subject>Endophthalmitis - etiology</subject><subject>Female</subject><subject>Human mycoses</subject><subject>Humans</subject><subject>Infant</subject><subject>Infectious diseases</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Mycoses</subject><subject>Mycoses of the eye and the orbit</subject><subject>Retina - microbiology</subject><subject>Tomography, X-Ray Computed</subject><subject>Vitreous Body - microbiology</subject><issn>0008-543X</issn><issn>1097-0142</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1984</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVUV2LFDEQHEQ519OfIORBRB9m7SSTmcmeCMucHweHC56C4EPIzHRuIvNlknW5f2-WXRf0QfCpu6nqoqhKkorCkgKwVxRkkQLN2AsqywwE0JeCr-RrKqVYrdZXl2n1sfrESgaCg-TsDV_CstpcsPTmXrI4fd9PFgBQpiLjXx8mj7z_Hs-CCX6WnOUZ4yzPF0l3ab3HwY46YEu0n9Hd2r6fvPVkduhxDHa8JTsbOoJjO81d6HQ_2GD9iqxJoz0Sh_PkAtFjFIjHT4s7MhkSOiS9Deh02Dp8nDwwuvf45DjPky_v3n6uPqTXm_dX1fo6bTJZstQAcM0lbVrKhSl5aaQRcS_AQDQsjOY8M6VEKLHN8oLXpWx0LdpaZ5jXkp8nzw-6s5t-bNEHNVjfYN_rEaetV2WMWAqRR-K3A7Fxk_cOjZqdHbS7UxTUvge1T1Ltk1S_e1CCK6n2PSgVe1B_9qC4AlVtFFM3Uf3p0ca2HrA9aR-Dj_izI659o3vj9NhYf6JJIWlBIdLMgbazPd79n8N_GvwL4b8AfXKzpw</recordid><startdate>19840501</startdate><enddate>19840501</enddate><creator>Demicco, Deborah D.</creator><creator>Reichman, Richard C.</creator><creator>Violette, E. 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Jeffrey ; Winn, Washington C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4982-f003a391cd135f838f9f5d1370f02665fa334f89e08ed4673b89cab5dba4e6b93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1984</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aspergillosis - diagnosis</topic><topic>Aspergillus flavus - growth & development</topic><topic>Biological and medical sciences</topic><topic>Brain Abscess - diagnostic imaging</topic><topic>Brain Abscess - etiology</topic><topic>Child</topic><topic>Endophthalmitis - diagnosis</topic><topic>Endophthalmitis - etiology</topic><topic>Female</topic><topic>Human mycoses</topic><topic>Humans</topic><topic>Infant</topic><topic>Infectious diseases</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Mycoses</topic><topic>Mycoses of the eye and the orbit</topic><topic>Retina - microbiology</topic><topic>Tomography, X-Ray Computed</topic><topic>Vitreous Body - microbiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Demicco, Deborah D.</creatorcontrib><creatorcontrib>Reichman, Richard C.</creatorcontrib><creatorcontrib>Violette, E. Jeffrey</creatorcontrib><creatorcontrib>Winn, Washington C.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Cancer</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Demicco, Deborah D.</au><au>Reichman, Richard C.</au><au>Violette, E. Jeffrey</au><au>Winn, Washington C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Disseminated aspergillosis presenting with endophthalmitis: A case report and a review of the literature</atitle><jtitle>Cancer</jtitle><addtitle>Cancer</addtitle><date>1984-05-01</date><risdate>1984</risdate><volume>53</volume><issue>9</issue><spage>1995</spage><epage>2001</epage><pages>1995-2001</pages><issn>0008-543X</issn><eissn>1097-0142</eissn><coden>CANCAR</coden><abstract>A patient with idiopathic thrombocytosis developed sudden loss of vision in his left eye secondary to endophthalmitis caused by Aspergillus flavus. He subsequently manifested other symptoms and signs of disseminated infection, and eventually died despite prompt initiation of appropriate parenteral antifungal therapy. A period of profound, iatrogenic neutropenia preceded the development of his terminal infection. Previously reported cases of hematogenously acquired Aspergillus endophthalmitis are reviewed, and approaches to diagnosis and management are discussed. The frequency of eye involvement in cases of disseminated aspergillosis is unknown, but it may be greater than appreciated previously.</abstract><cop>New York</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>6423266</pmid><doi>10.1002/1097-0142(19840501)53:9<1995::AID-CNCR2820530932>3.0.CO;2-S</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0008-543X |
| ispartof | Cancer, 1984-05, Vol.53 (9), p.1995-2001 |
| issn | 0008-543X 1097-0142 |
| language | eng |
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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Adolescent Adult Aged Aspergillosis - diagnosis Aspergillus flavus - growth & development Biological and medical sciences Brain Abscess - diagnostic imaging Brain Abscess - etiology Child Endophthalmitis - diagnosis Endophthalmitis - etiology Female Human mycoses Humans Infant Infectious diseases Male Medical sciences Middle Aged Mycoses Mycoses of the eye and the orbit Retina - microbiology Tomography, X-Ray Computed Vitreous Body - microbiology |
| title | Disseminated aspergillosis presenting with endophthalmitis: A case report and a review of the literature |
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