HL-T, A New Cell Line Derived From HL-60 Promyelocytic Leukemia Cell Cultures Expressing Terminal Transferase and Secreting Suppressor Activity

A cell line with immature blast cell morphology was isolated from HL-60 promyelocytic leukemia cell cultures and designated HL-T. This new cell type is biphenotypic, expressing terminal transferase (TdT) together with myelomonocytoid immunologic features. TdT enzymatic activity, undetectable in HL-6...

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Veröffentlicht in:	Blood 1987-10, Vol.70 (4), p.1151-1160
Hauptverfasser:	Paietta, Elisabeth, Stockert, Richard J., Calvelli, Theresa, Papenhausen, Peter, Seremetis, Stephanie V., Fotino, Marilena, Wiernik, Peter H., Chang, Lucy, Bollum, Fred J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cell Line Chromosome Aberrations Genes Hematologic and hematopoietic diseases Humans Immunologic Techniques Karyotyping Leukemia, Myeloid, Acute - enzymology Leukemia, Myeloid, Acute - genetics Leukemia, Myeloid, Acute - pathology Leukemia, Myeloid, Acute - physiopathology Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Medical sciences Phenotype Suppressor Factors, Immunologic - metabolism Transferases - metabolism
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