Use of intravenous immune globulin in pregnant women with common variable hypogammaglobulinemia
Two patients with common variable hypogammaglobulinemia were treated with immune serum globulin during pregnancy. An intravenous immune serum globulin preparation was used in the last trimester of pregnancy. Both patients tolerated this preparation well and had an uneventful pregnancy. The two term...
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Veröffentlicht in: | The American journal of medicine 1984-03, Vol.76 (3), p.73-77 |
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creator | Sorensen, Ricardo U. Tomford, J.Walton Gyves, Michael T. Judge, Nancy E. Polmar, Stephen H. |
description | Two patients with common variable hypogammaglobulinemia were treated with immune serum globulin during pregnancy. An intravenous immune serum globulin preparation was used in the last trimester of pregnancy. Both patients tolerated this preparation well and had an uneventful pregnancy. The two term newborns were healthy and had cord blood IgG levels likely to be the result of transplacental transfer of the intravenous immune serum globulin preparation. During pregnancy there is an increase in the IgG distribution space due to plasma volume expansion. Therefore, pregnancy is an indication for these immune serum globulin preparations that can be administered at high doses intravenously in order to confer adequate protection to the mother and the newborn. |
doi_str_mv | 10.1016/0002-9343(84)90323-1 |
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An intravenous immune serum globulin preparation was used in the last trimester of pregnancy. Both patients tolerated this preparation well and had an uneventful pregnancy. The two term newborns were healthy and had cord blood IgG levels likely to be the result of transplacental transfer of the intravenous immune serum globulin preparation. During pregnancy there is an increase in the IgG distribution space due to plasma volume expansion. Therefore, pregnancy is an indication for these immune serum globulin preparations that can be administered at high doses intravenously in order to confer adequate protection to the mother and the newborn.</description><identifier>ISSN: 0002-9343</identifier><identifier>EISSN: 1555-7162</identifier><identifier>DOI: 10.1016/0002-9343(84)90323-1</identifier><identifier>PMID: 6424460</identifier><identifier>CODEN: AJMEAZ</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adolescent ; Adult ; Agammaglobulinemia - immunology ; Agammaglobulinemia - physiopathology ; Agammaglobulinemia - therapy ; Biological and medical sciences ; Female ; Fetal Blood - immunology ; Humans ; Immunity, Maternally-Acquired ; Immunodeficiencies. Immunoglobulinopathies ; Immunoglobulin G - administration & dosage ; Immunoglobulin G - analogs & derivatives ; Immunoglobulin G - metabolism ; Immunoglobulinopathies ; Immunoglobulins, Intravenous ; Immunopathology ; Infant ; Infant, Newborn ; Medical sciences ; Pregnancy ; Pregnancy Complications - immunology ; Pregnancy Complications - therapy</subject><ispartof>The American journal of medicine, 1984-03, Vol.76 (3), p.73-77</ispartof><rights>1984</rights><rights>1984 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c386t-f38a7a92d8b5bc9ad450741f860b2c2919183b8a829697808b51434232a1e8cd3</citedby><cites>FETCH-LOGICAL-c386t-f38a7a92d8b5bc9ad450741f860b2c2919183b8a829697808b51434232a1e8cd3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0002-9343(84)90323-1$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=9538763$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6424460$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sorensen, Ricardo U.</creatorcontrib><creatorcontrib>Tomford, J.Walton</creatorcontrib><creatorcontrib>Gyves, Michael T.</creatorcontrib><creatorcontrib>Judge, Nancy E.</creatorcontrib><creatorcontrib>Polmar, Stephen H.</creatorcontrib><title>Use of intravenous immune globulin in pregnant women with common variable hypogammaglobulinemia</title><title>The American journal of medicine</title><addtitle>Am J Med</addtitle><description>Two patients with common variable hypogammaglobulinemia were treated with immune serum globulin during pregnancy. An intravenous immune serum globulin preparation was used in the last trimester of pregnancy. Both patients tolerated this preparation well and had an uneventful pregnancy. The two term newborns were healthy and had cord blood IgG levels likely to be the result of transplacental transfer of the intravenous immune serum globulin preparation. During pregnancy there is an increase in the IgG distribution space due to plasma volume expansion. Therefore, pregnancy is an indication for these immune serum globulin preparations that can be administered at high doses intravenously in order to confer adequate protection to the mother and the newborn.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Agammaglobulinemia - immunology</subject><subject>Agammaglobulinemia - physiopathology</subject><subject>Agammaglobulinemia - therapy</subject><subject>Biological and medical sciences</subject><subject>Female</subject><subject>Fetal Blood - immunology</subject><subject>Humans</subject><subject>Immunity, Maternally-Acquired</subject><subject>Immunodeficiencies. Immunoglobulinopathies</subject><subject>Immunoglobulin G - administration & dosage</subject><subject>Immunoglobulin G - analogs & derivatives</subject><subject>Immunoglobulin G - metabolism</subject><subject>Immunoglobulinopathies</subject><subject>Immunoglobulins, Intravenous</subject><subject>Immunopathology</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Medical sciences</subject><subject>Pregnancy</subject><subject>Pregnancy Complications - immunology</subject><subject>Pregnancy Complications - therapy</subject><issn>0002-9343</issn><issn>1555-7162</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1984</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE2LFDEQhoMo6-zqP1DIQUQPrfnqdHIRZHFVWPDinkN1uno20knGpHuW_ff2OOMcPRXhfd6i8hDyirMPnHH9kTEmGiuVfGfUe8ukkA1_Qja8bdum41o8JZsz8pxc1vprfTLb6gtyoZVQSrMNcXcVaR5pSHOBPaa8VBpiXBLS7ZT7ZQppzeiu4DZBmulDjpjoQ5jvqc8x5kT3UAL0E9L7x13eQozwr4gxwAvybISp4svTvCJ3N19-Xn9rbn98_X79-bbx0ui5GaWBDqwYTN_23sKgWtYpPhrNeuGF5ZYb2RswwmrbGbZiXEklpACOxg_yirw97t2V_HvBOrsYqsdpgoTrn5zhjGkmxAqqI-hLrrXg6HYlRCiPjjN38OoO0txBmjPK_fXq-Fp7fdq_9BGHc-kkcs3fnHKoHqaxQPKhnjHbStNpuWKfjhiuLvYBi6s-YPI4hIJ-dkMO_7_jD7G-lDE</recordid><startdate>19840330</startdate><enddate>19840330</enddate><creator>Sorensen, Ricardo U.</creator><creator>Tomford, J.Walton</creator><creator>Gyves, Michael T.</creator><creator>Judge, Nancy E.</creator><creator>Polmar, Stephen H.</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19840330</creationdate><title>Use of intravenous immune globulin in pregnant women with common variable hypogammaglobulinemia</title><author>Sorensen, Ricardo U. ; Tomford, J.Walton ; Gyves, Michael T. ; Judge, Nancy E. ; Polmar, Stephen H.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c386t-f38a7a92d8b5bc9ad450741f860b2c2919183b8a829697808b51434232a1e8cd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1984</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Agammaglobulinemia - immunology</topic><topic>Agammaglobulinemia - physiopathology</topic><topic>Agammaglobulinemia - therapy</topic><topic>Biological and medical sciences</topic><topic>Female</topic><topic>Fetal Blood - immunology</topic><topic>Humans</topic><topic>Immunity, Maternally-Acquired</topic><topic>Immunodeficiencies. Immunoglobulinopathies</topic><topic>Immunoglobulin G - administration & dosage</topic><topic>Immunoglobulin G - analogs & derivatives</topic><topic>Immunoglobulin G - metabolism</topic><topic>Immunoglobulinopathies</topic><topic>Immunoglobulins, Intravenous</topic><topic>Immunopathology</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Medical sciences</topic><topic>Pregnancy</topic><topic>Pregnancy Complications - immunology</topic><topic>Pregnancy Complications - therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sorensen, Ricardo U.</creatorcontrib><creatorcontrib>Tomford, J.Walton</creatorcontrib><creatorcontrib>Gyves, Michael T.</creatorcontrib><creatorcontrib>Judge, Nancy E.</creatorcontrib><creatorcontrib>Polmar, Stephen H.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sorensen, Ricardo U.</au><au>Tomford, J.Walton</au><au>Gyves, Michael T.</au><au>Judge, Nancy E.</au><au>Polmar, Stephen H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Use of intravenous immune globulin in pregnant women with common variable hypogammaglobulinemia</atitle><jtitle>The American journal of medicine</jtitle><addtitle>Am J Med</addtitle><date>1984-03-30</date><risdate>1984</risdate><volume>76</volume><issue>3</issue><spage>73</spage><epage>77</epage><pages>73-77</pages><issn>0002-9343</issn><eissn>1555-7162</eissn><coden>AJMEAZ</coden><abstract>Two patients with common variable hypogammaglobulinemia were treated with immune serum globulin during pregnancy. An intravenous immune serum globulin preparation was used in the last trimester of pregnancy. Both patients tolerated this preparation well and had an uneventful pregnancy. The two term newborns were healthy and had cord blood IgG levels likely to be the result of transplacental transfer of the intravenous immune serum globulin preparation. During pregnancy there is an increase in the IgG distribution space due to plasma volume expansion. Therefore, pregnancy is an indication for these immune serum globulin preparations that can be administered at high doses intravenously in order to confer adequate protection to the mother and the newborn.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>6424460</pmid><doi>10.1016/0002-9343(84)90323-1</doi><tpages>5</tpages></addata></record> |
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subjects | Adolescent Adult Agammaglobulinemia - immunology Agammaglobulinemia - physiopathology Agammaglobulinemia - therapy Biological and medical sciences Female Fetal Blood - immunology Humans Immunity, Maternally-Acquired Immunodeficiencies. Immunoglobulinopathies Immunoglobulin G - administration & dosage Immunoglobulin G - analogs & derivatives Immunoglobulin G - metabolism Immunoglobulinopathies Immunoglobulins, Intravenous Immunopathology Infant Infant, Newborn Medical sciences Pregnancy Pregnancy Complications - immunology Pregnancy Complications - therapy |
title | Use of intravenous immune globulin in pregnant women with common variable hypogammaglobulinemia |
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