A physiologically based description of the inhalation pharmacokinetics of styrene in rats and humans

A physiologically based pharmacokinetic model which describes the behavior of inhaled styrene in rats accurately predicts the behavior of inhaled styrene in humans. The model consists of a series of mass-balance differential equations which quantify the time course of styrene concentration within fo...

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Veröffentlicht in:	Toxicology and applied pharmacology 1984-03, Vol.73 (1), p.159-175
Hauptverfasser:	Ramsey, John C., Andersen, Melvin E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Animals Biological and medical sciences Chemical and industrial products toxicology. Toxic occupational diseases Gases Humans Injections, Intravenous Kinetics Liver - metabolism Lung - metabolism Male Medical sciences Models, Biological Rats Rats, Inbred Strains Solvents Species Specificity Styrene Styrenes - metabolism Toxicology
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