Polymorphonuclear leukocyte function in psoriasis vulgaris
SUMMARY Polymorphonuclear leukocyte (PMN) migration was assessed in vitro using the agarose plate method in patients with psoriasis vulgaris, and compared with an age‐ and sex‐matched control group. No significant difference was found between the two groups in the PMN response to the chemotactic sub...
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Veröffentlicht in: | British journal of dermatology (1951) 1987-08, Vol.117 (2), p.161-167 |
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container_title | British journal of dermatology (1951) |
container_volume | 117 |
creator | PEASE, C.T. FENNELL, M. STAUGHTON, R.C.D. BREWERTON, D.A. |
description | SUMMARY
Polymorphonuclear leukocyte (PMN) migration was assessed in vitro using the agarose plate method in patients with psoriasis vulgaris, and compared with an age‐ and sex‐matched control group. No significant difference was found between the two groups in the PMN response to the chemotactic substances F–Met–Leu‐fPhe (FMLP) or zymosan activated serum (ZAS). Equally, the chemokinetic or chemotactic potential of psoriatic serum did not differ from control serum. Our results do not support a primary abnormality of PMN function in psoriasis. |
doi_str_mv | 10.1111/j.1365-2133.1987.tb04112.x |
format | Article |
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Polymorphonuclear leukocyte (PMN) migration was assessed in vitro using the agarose plate method in patients with psoriasis vulgaris, and compared with an age‐ and sex‐matched control group. No significant difference was found between the two groups in the PMN response to the chemotactic substances F–Met–Leu‐fPhe (FMLP) or zymosan activated serum (ZAS). Equally, the chemokinetic or chemotactic potential of psoriatic serum did not differ from control serum. Our results do not support a primary abnormality of PMN function in psoriasis.</description><identifier>ISSN: 0007-0963</identifier><identifier>EISSN: 1365-2133</identifier><identifier>DOI: 10.1111/j.1365-2133.1987.tb04112.x</identifier><identifier>PMID: 3651338</identifier><identifier>CODEN: BJDEAZ</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Arthritis - blood ; Biological and medical sciences ; Cell Movement ; Chemotaxis, Leukocyte ; Dermatology ; Female ; Humans ; In Vitro Techniques ; Male ; Medical sciences ; Neutrophils - physiology ; Psoriasis - blood ; Psoriasis. Parapsoriasis. Lichen</subject><ispartof>British journal of dermatology (1951), 1987-08, Vol.117 (2), p.161-167</ispartof><rights>1987 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4361-fe6037628c8d84b34863894aa69b390c5aa3585f510c22729bc4a2c3c91e7dba3</citedby><cites>FETCH-LOGICAL-c4361-fe6037628c8d84b34863894aa69b390c5aa3585f510c22729bc4a2c3c91e7dba3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1365-2133.1987.tb04112.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1365-2133.1987.tb04112.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8307567$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3651338$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>PEASE, C.T.</creatorcontrib><creatorcontrib>FENNELL, M.</creatorcontrib><creatorcontrib>STAUGHTON, R.C.D.</creatorcontrib><creatorcontrib>BREWERTON, D.A.</creatorcontrib><title>Polymorphonuclear leukocyte function in psoriasis vulgaris</title><title>British journal of dermatology (1951)</title><addtitle>Br J Dermatol</addtitle><description>SUMMARY
Polymorphonuclear leukocyte (PMN) migration was assessed in vitro using the agarose plate method in patients with psoriasis vulgaris, and compared with an age‐ and sex‐matched control group. No significant difference was found between the two groups in the PMN response to the chemotactic substances F–Met–Leu‐fPhe (FMLP) or zymosan activated serum (ZAS). Equally, the chemokinetic or chemotactic potential of psoriatic serum did not differ from control serum. Our results do not support a primary abnormality of PMN function in psoriasis.</description><subject>Arthritis - blood</subject><subject>Biological and medical sciences</subject><subject>Cell Movement</subject><subject>Chemotaxis, Leukocyte</subject><subject>Dermatology</subject><subject>Female</subject><subject>Humans</subject><subject>In Vitro Techniques</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Neutrophils - physiology</subject><subject>Psoriasis - blood</subject><subject>Psoriasis. Parapsoriasis. Lichen</subject><issn>0007-0963</issn><issn>1365-2133</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1987</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkM1O4zAUhS0EgsLMIyBFCLFLsOP4JyyQoPwMCM2MNKAiNpbjOuDixsVOoH37cdSoe7zx4nz3-PoD4AjBDMVzOssQpiTNEcYZKjnL2goWCOXZcguMNtE2GEEIWQpLivfAfggzCBGGBO6C3chEgo_A2V9nV3PnF2-u6ZTV0idWd-9OrVqd1F2jWuOaxDTJIjhvZDAh-ezsq_Qm_AA7tbRB_xzuA_B0c_04_pU-_Lm9G188pKrAFKW1phAzmnPFp7yocMEp5mUhJS0rXEJFpMSEk5ogqPKc5WWlCpkrrEqk2bSS-ACcrHsX3n10OrRiboLS1spGuy4IjmD_TxrBszWovAvB61osvJlLvxIIil6cmInejujtiF6cGMSJZRw-HF7pqrmebkYHUzE_HnIZlLS1l40yYYNxDBmhLGLna-zLWL36xgLi8v4KURQL0nWBCa1ebgqkfxexnhEx-X0r2At5fiT_JmKC_wNDpZlt</recordid><startdate>198708</startdate><enddate>198708</enddate><creator>PEASE, C.T.</creator><creator>FENNELL, M.</creator><creator>STAUGHTON, R.C.D.</creator><creator>BREWERTON, D.A.</creator><general>Blackwell Publishing Ltd</general><general>Blackwell</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198708</creationdate><title>Polymorphonuclear leukocyte function in psoriasis vulgaris</title><author>PEASE, C.T. ; FENNELL, M. ; STAUGHTON, R.C.D. ; BREWERTON, D.A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4361-fe6037628c8d84b34863894aa69b390c5aa3585f510c22729bc4a2c3c91e7dba3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1987</creationdate><topic>Arthritis - blood</topic><topic>Biological and medical sciences</topic><topic>Cell Movement</topic><topic>Chemotaxis, Leukocyte</topic><topic>Dermatology</topic><topic>Female</topic><topic>Humans</topic><topic>In Vitro Techniques</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Neutrophils - physiology</topic><topic>Psoriasis - blood</topic><topic>Psoriasis. Parapsoriasis. Lichen</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>PEASE, C.T.</creatorcontrib><creatorcontrib>FENNELL, M.</creatorcontrib><creatorcontrib>STAUGHTON, R.C.D.</creatorcontrib><creatorcontrib>BREWERTON, D.A.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>British journal of dermatology (1951)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>PEASE, C.T.</au><au>FENNELL, M.</au><au>STAUGHTON, R.C.D.</au><au>BREWERTON, D.A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Polymorphonuclear leukocyte function in psoriasis vulgaris</atitle><jtitle>British journal of dermatology (1951)</jtitle><addtitle>Br J Dermatol</addtitle><date>1987-08</date><risdate>1987</risdate><volume>117</volume><issue>2</issue><spage>161</spage><epage>167</epage><pages>161-167</pages><issn>0007-0963</issn><eissn>1365-2133</eissn><coden>BJDEAZ</coden><abstract>SUMMARY
Polymorphonuclear leukocyte (PMN) migration was assessed in vitro using the agarose plate method in patients with psoriasis vulgaris, and compared with an age‐ and sex‐matched control group. No significant difference was found between the two groups in the PMN response to the chemotactic substances F–Met–Leu‐fPhe (FMLP) or zymosan activated serum (ZAS). Equally, the chemokinetic or chemotactic potential of psoriatic serum did not differ from control serum. Our results do not support a primary abnormality of PMN function in psoriasis.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>3651338</pmid><doi>10.1111/j.1365-2133.1987.tb04112.x</doi><tpages>7</tpages></addata></record> |
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source | MEDLINE; Access via Wiley Online Library |
subjects | Arthritis - blood Biological and medical sciences Cell Movement Chemotaxis, Leukocyte Dermatology Female Humans In Vitro Techniques Male Medical sciences Neutrophils - physiology Psoriasis - blood Psoriasis. Parapsoriasis. Lichen |
title | Polymorphonuclear leukocyte function in psoriasis vulgaris |
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