Polymorphonuclear leukocyte function in psoriasis vulgaris

Polymorphonuclear leukocyte function in psoriasis vulgaris

SUMMARY Polymorphonuclear leukocyte (PMN) migration was assessed in vitro using the agarose plate method in patients with psoriasis vulgaris, and compared with an age‐ and sex‐matched control group. No significant difference was found between the two groups in the PMN response to the chemotactic sub...

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Veröffentlicht in:British journal of dermatology (1951) 1987-08, Vol.117 (2), p.161-167
Hauptverfasser: PEASE, C.T., FENNELL, M., STAUGHTON, R.C.D., BREWERTON, D.A.
Format: Artikel
Sprache:eng
Schlagworte:
Arthritis - blood
Biological and medical sciences
Cell Movement
Chemotaxis, Leukocyte
Dermatology
Female
Humans
In Vitro Techniques
Male
Medical sciences
Neutrophils - physiology
Psoriasis - blood
Psoriasis. Parapsoriasis. Lichen
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Zusammenfassung:SUMMARY Polymorphonuclear leukocyte (PMN) migration was assessed in vitro using the agarose plate method in patients with psoriasis vulgaris, and compared with an age‐ and sex‐matched control group. No significant difference was found between the two groups in the PMN response to the chemotactic substances F–Met–Leu‐fPhe (FMLP) or zymosan activated serum (ZAS). Equally, the chemokinetic or chemotactic potential of psoriatic serum did not differ from control serum. Our results do not support a primary abnormality of PMN function in psoriasis.
ISSN:0007-0963
1365-2133
DOI:10.1111/j.1365-2133.1987.tb04112.x