Prophylactic Metronidazole or Suction Drainage in Abdominal Hysterectomy
The efficacy of a two-dose perioperative course of oral metronidazole or suction drainage of the vaginal vault was evaluated in a randomized study of 150 patients undergoing abdominal hysterectomy. Patients receiving metronidazole demonstrated a significant reduction in febrile morbidity (from 48 to...
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| Veröffentlicht in: | Obstetrics and gynecology (New York. 1953) 1984-03, Vol.63 (3), p.291-294 |
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| container_title | Obstetrics and gynecology (New York. 1953) |
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| creator | POULSEN, HENNING KVIST BOREL, JOHN OLSEN, HELGE |
| description | The efficacy of a two-dose perioperative course of oral metronidazole or suction drainage of the vaginal vault was evaluated in a randomized study of 150 patients undergoing abdominal hysterectomy. Patients receiving metronidazole demonstrated a significant reduction in febrile morbidity (from 48 to 8%), infectious morbidity (from 46 to 16%), urinary tract infections (from 30 to 10%), and pelvic and/or abdominal wound infections (from 18 to 2%). The patients managed with suction drainage showed a marked reduction in febrile and infectious morbidity; however, this reduction was not significant. Overall, 17% of all specific postoperative infections were first diagnosed after discharge from the hospital. No adverse side effects of metronidazole were encountered. |
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Patients receiving metronidazole demonstrated a significant reduction in febrile morbidity (from 48 to 8%), infectious morbidity (from 46 to 16%), urinary tract infections (from 30 to 10%), and pelvic and/or abdominal wound infections (from 18 to 2%). The patients managed with suction drainage showed a marked reduction in febrile and infectious morbidity; however, this reduction was not significant. Overall, 17% of all specific postoperative infections were first diagnosed after discharge from the hospital. No adverse side effects of metronidazole were encountered.</description><identifier>ISSN: 0029-7844</identifier><identifier>EISSN: 1873-233X</identifier><identifier>PMID: 6700850</identifier><identifier>CODEN: OBGNAS</identifier><language>eng</language><publisher>New York, NY: The American College of Obstetricians and Gynecologists</publisher><subject>Adult ; Aged ; Antibacterial agents ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Bacterial Infections - prevention & control ; Biological and medical sciences ; Female ; Fever - prevention & control ; Humans ; Hysterectomy ; Medical sciences ; Metronidazole - administration & dosage ; Middle Aged ; Pharmacology. Drug treatments ; Postoperative Care ; Premedication ; Preoperative Care ; Random Allocation ; Suction ; Surgical Wound Infection - prevention & control ; Urinary Tract Infections - prevention & control</subject><ispartof>Obstetrics and gynecology (New York. 1953), 1984-03, Vol.63 (3), p.291-294</ispartof><rights>1984 The American College of Obstetricians and Gynecologists</rights><rights>1984 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=9556759$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6700850$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>POULSEN, HENNING KVIST</creatorcontrib><creatorcontrib>BOREL, JOHN</creatorcontrib><creatorcontrib>OLSEN, HELGE</creatorcontrib><title>Prophylactic Metronidazole or Suction Drainage in Abdominal Hysterectomy</title><title>Obstetrics and gynecology (New York. 1953)</title><addtitle>Obstet Gynecol</addtitle><description>The efficacy of a two-dose perioperative course of oral metronidazole or suction drainage of the vaginal vault was evaluated in a randomized study of 150 patients undergoing abdominal hysterectomy. Patients receiving metronidazole demonstrated a significant reduction in febrile morbidity (from 48 to 8%), infectious morbidity (from 46 to 16%), urinary tract infections (from 30 to 10%), and pelvic and/or abdominal wound infections (from 18 to 2%). The patients managed with suction drainage showed a marked reduction in febrile and infectious morbidity; however, this reduction was not significant. Overall, 17% of all specific postoperative infections were first diagnosed after discharge from the hospital. No adverse side effects of metronidazole were encountered.</description><subject>Adult</subject><subject>Aged</subject><subject>Antibacterial agents</subject><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>Bacterial Infections - prevention & control</subject><subject>Biological and medical sciences</subject><subject>Female</subject><subject>Fever - prevention & control</subject><subject>Humans</subject><subject>Hysterectomy</subject><subject>Medical sciences</subject><subject>Metronidazole - administration & dosage</subject><subject>Middle Aged</subject><subject>Pharmacology. Drug treatments</subject><subject>Postoperative Care</subject><subject>Premedication</subject><subject>Preoperative Care</subject><subject>Random Allocation</subject><subject>Suction</subject><subject>Surgical Wound Infection - prevention & control</subject><subject>Urinary Tract Infections - prevention & control</subject><issn>0029-7844</issn><issn>1873-233X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1984</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kF1LwzAYhYMoc05_gtAL8a7wJs3n5ZgfEyYKKnhX0i511bSpScuov97Iilcv55yHF845QnMsRZaSLHs_RnMAolIhKT1FZyF8AgDmKpuhGRcAksEcrZ-963aj1WVfl8mj6b1r663-cdYkzicvQ_Rdm9x4Xbf6wyR1myyLrWuissl6DL3xpuxdM56jk0rbYC6mu0Bvd7evq3W6ebp_WC03aUcksJQyEJhCxYBVlAtZSE4oFAUpMUBFYiQYxpxqMDqapMJcGEG00gZjEDxboOvD386778GEPm_qUBprdWvcEHIJShEsswheTuBQNGabd75utB_zqXrMr6Zch1Lbyuu2rMM_phjjgqmI0QO2dzaWDV922Buf74y2_S6PiwInDFKsJIUsqvTPYtkvpsBw9w</recordid><startdate>198403</startdate><enddate>198403</enddate><creator>POULSEN, HENNING KVIST</creator><creator>BOREL, JOHN</creator><creator>OLSEN, HELGE</creator><general>The American College of Obstetricians and Gynecologists</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>198403</creationdate><title>Prophylactic Metronidazole or Suction Drainage in Abdominal Hysterectomy</title><author>POULSEN, HENNING KVIST ; BOREL, JOHN ; OLSEN, HELGE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p2805-4507140f505f4678b86240bb2c100f2140751164a0eab2c2f167e72a9ae110763</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1984</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Antibacterial agents</topic><topic>Antibiotics. Antiinfectious agents. Antiparasitic agents</topic><topic>Bacterial Infections - prevention & control</topic><topic>Biological and medical sciences</topic><topic>Female</topic><topic>Fever - prevention & control</topic><topic>Humans</topic><topic>Hysterectomy</topic><topic>Medical sciences</topic><topic>Metronidazole - administration & dosage</topic><topic>Middle Aged</topic><topic>Pharmacology. Drug treatments</topic><topic>Postoperative Care</topic><topic>Premedication</topic><topic>Preoperative Care</topic><topic>Random Allocation</topic><topic>Suction</topic><topic>Surgical Wound Infection - prevention & control</topic><topic>Urinary Tract Infections - prevention & control</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>POULSEN, HENNING KVIST</creatorcontrib><creatorcontrib>BOREL, JOHN</creatorcontrib><creatorcontrib>OLSEN, HELGE</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Obstetrics and gynecology (New York. 1953)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>POULSEN, HENNING KVIST</au><au>BOREL, JOHN</au><au>OLSEN, HELGE</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prophylactic Metronidazole or Suction Drainage in Abdominal Hysterectomy</atitle><jtitle>Obstetrics and gynecology (New York. 1953)</jtitle><addtitle>Obstet Gynecol</addtitle><date>1984-03</date><risdate>1984</risdate><volume>63</volume><issue>3</issue><spage>291</spage><epage>294</epage><pages>291-294</pages><issn>0029-7844</issn><eissn>1873-233X</eissn><coden>OBGNAS</coden><abstract>The efficacy of a two-dose perioperative course of oral metronidazole or suction drainage of the vaginal vault was evaluated in a randomized study of 150 patients undergoing abdominal hysterectomy. Patients receiving metronidazole demonstrated a significant reduction in febrile morbidity (from 48 to 8%), infectious morbidity (from 46 to 16%), urinary tract infections (from 30 to 10%), and pelvic and/or abdominal wound infections (from 18 to 2%). The patients managed with suction drainage showed a marked reduction in febrile and infectious morbidity; however, this reduction was not significant. Overall, 17% of all specific postoperative infections were first diagnosed after discharge from the hospital. No adverse side effects of metronidazole were encountered.</abstract><cop>New York, NY</cop><pub>The American College of Obstetricians and Gynecologists</pub><pmid>6700850</pmid><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0029-7844 |
| ispartof | Obstetrics and gynecology (New York. 1953), 1984-03, Vol.63 (3), p.291-294 |
| issn | 0029-7844 1873-233X |
| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Adult Aged Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Bacterial Infections - prevention & control Biological and medical sciences Female Fever - prevention & control Humans Hysterectomy Medical sciences Metronidazole - administration & dosage Middle Aged Pharmacology. Drug treatments Postoperative Care Premedication Preoperative Care Random Allocation Suction Surgical Wound Infection - prevention & control Urinary Tract Infections - prevention & control |
| title | Prophylactic Metronidazole or Suction Drainage in Abdominal Hysterectomy |
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