Specific leukotriene formation by purified human eosinophils and neutrophils

Human granulocytes isolated from peripheral blood have been described to synthesize both LTB 4 and LTC 4 from arachidonic acid. We have observed that the amount of LTC 4 produced by human granulocyte preparations is strongly dependent on the relative amount of eosinophils. To investigate a possibly...

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Veröffentlicht in:FEBS letters 1984-03, Vol.168 (1), p.23-28
Hauptverfasser: Verhagen, Jan, Bruynzeel, Pieter L.B., Koedam, Johannes A., Aryan Wassink, G., de Boer, Martin, Terpstra, Gerben K., Kreukniet, Johannes, Veldink, Gerrit A., Vliegenthart, Johannes F.G.
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