The functional human dihydrofolate reductase gene

Molecular cloning, mapping, and DNA sequencing techniques have been used to characterize the functional human dihydrofolate reductase (DHFR) gene. The gene is about 30 kilobases in length. Its coding portions are separated into 6 exons, the intron-exon boundaries of which are identical to those of t...

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Veröffentlicht in:	The Journal of biological chemistry 1984-03, Vol.259 (6), p.3933-3943
Hauptverfasser:	Chen, M J, Shimada, T, Moulton, A D, Cline, A, Humphries, R K, Maizel, J, Nienhuis, A W
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Biological and medical sciences Cloning, Molecular DNA - analysis DNA Restriction Enzymes Fundamental and applied biological sciences. Psychology Genes Genes. Genome Genetic Vectors HeLa Cells Humans Molecular and cellular biology Molecular genetics Nucleic Acid Hybridization Plasmids Tetrahydrofolate Dehydrogenase - genetics Transcription, Genetic Transfection
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