Feline Leukaemia Viral Antigens and Antisera to the Group Specific Antigens of the Murine Leukaemia Viruses

GEERING et al.1 reported that feline leukaemia viruses shared one of the group specific antigens of the murine leukaemia viruses, gs-3, as detected by immunoprecipitation in agar gels with broadly reactive rat antisera to the group specific antigens of the murine leukaemia viruses (MuLV). Subsequent...

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Veröffentlicht in:Nature (London) 1971-03, Vol.230 (10), p.50-52
Hauptverfasser: SARMA, PADMAN S, HUEBNER, ROBERT J, TURNER, HORACE C, GILDEN, RAYMOND V, LOG, TZE-SIUNG
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container_end_page 52
container_issue 10
container_start_page 50
container_title Nature (London)
container_volume 230
creator SARMA, PADMAN S
HUEBNER, ROBERT J
TURNER, HORACE C
GILDEN, RAYMOND V
LOG, TZE-SIUNG
description GEERING et al.1 reported that feline leukaemia viruses shared one of the group specific antigens of the murine leukaemia viruses, gs-3, as detected by immunoprecipitation in agar gels with broadly reactive rat antisera to the group specific antigens of the murine leukaemia viruses (MuLV). Subsequently, they found that this shared group specific antigen was also present in the hamster and rat C-type viruses2. Work by Schafer3 and our own immunodiffusion4 and complement fixation studies have confirmed the immunological reactivity between the feline leukaemia viral antigens and broad-reacting murine leukaemia group specific antisera. We have now applied this interspecies immunological reaction between the murine and feline C-type viruses to quantitative studies of the feline leukaemia viruses. Broad-reactive murine leukaemia-sarcoma group specific antisera prepared in rats by the induction of murine sarcoma virus (MSV) tumours5, 6 were found to be as useful and nearly as sensitive as a feline leukaemia-sarcoma specific, group specific antiserum for the in vitro detection and assay of the noncytopathogenic feline leukaemia virus (FeLV).
doi_str_mv 10.1038/newbio230050a0
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Broad-reactive murine leukaemia-sarcoma group specific antisera prepared in rats by the induction of murine sarcoma virus (MSV) tumours5, 6 were found to be as useful and nearly as sensitive as a feline leukaemia-sarcoma specific, group specific antiserum for the in vitro detection and assay of the noncytopathogenic feline leukaemia virus (FeLV).</description><identifier>ISSN: 0028-0836</identifier><identifier>ISSN: 0090-0028</identifier><identifier>EISSN: 1476-4687</identifier><identifier>EISSN: 2058-1092</identifier><identifier>DOI: 10.1038/newbio230050a0</identifier><identifier>PMID: 5279807</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>Animals ; Antigens - analysis ; Biomedical and Life Sciences ; Cat Diseases - microbiology ; Cats ; Complement Fixation Tests ; Immune Sera ; letters-to-editor ; Leukemia - veterinary ; Life Sciences ; Mice ; Moloney murine leukemia virus - immunology ; Retroviridae - immunology</subject><ispartof>Nature (London), 1971-03, Vol.230 (10), p.50-52</ispartof><rights>Springer Nature Limited 1971</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c359t-8718b78a929c4e9dd8d4aa7a5476ab8f96e378b2f22977b5bfa4a211c94739da3</citedby><cites>FETCH-LOGICAL-c359t-8718b78a929c4e9dd8d4aa7a5476ab8f96e378b2f22977b5bfa4a211c94739da3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,2727,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/5279807$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>SARMA, PADMAN S</creatorcontrib><creatorcontrib>HUEBNER, ROBERT J</creatorcontrib><creatorcontrib>TURNER, HORACE C</creatorcontrib><creatorcontrib>GILDEN, RAYMOND V</creatorcontrib><creatorcontrib>LOG, TZE-SIUNG</creatorcontrib><title>Feline Leukaemia Viral Antigens and Antisera to the Group Specific Antigens of the Murine Leukaemia Viruses</title><title>Nature (London)</title><addtitle>Nature New Biology</addtitle><addtitle>Nat New Biol</addtitle><description>GEERING et al.1 reported that feline leukaemia viruses shared one of the group specific antigens of the murine leukaemia viruses, gs-3, as detected by immunoprecipitation in agar gels with broadly reactive rat antisera to the group specific antigens of the murine leukaemia viruses (MuLV). Subsequently, they found that this shared group specific antigen was also present in the hamster and rat C-type viruses2. Work by Schafer3 and our own immunodiffusion4 and complement fixation studies have confirmed the immunological reactivity between the feline leukaemia viral antigens and broad-reacting murine leukaemia group specific antisera. We have now applied this interspecies immunological reaction between the murine and feline C-type viruses to quantitative studies of the feline leukaemia viruses. 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subjects Animals
Antigens - analysis
Biomedical and Life Sciences
Cat Diseases - microbiology
Cats
Complement Fixation Tests
Immune Sera
letters-to-editor
Leukemia - veterinary
Life Sciences
Mice
Moloney murine leukemia virus - immunology
Retroviridae - immunology
title Feline Leukaemia Viral Antigens and Antisera to the Group Specific Antigens of the Murine Leukaemia Viruses
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