Feline Leukaemia Viral Antigens and Antisera to the Group Specific Antigens of the Murine Leukaemia Viruses
GEERING et al.1 reported that feline leukaemia viruses shared one of the group specific antigens of the murine leukaemia viruses, gs-3, as detected by immunoprecipitation in agar gels with broadly reactive rat antisera to the group specific antigens of the murine leukaemia viruses (MuLV). Subsequent...
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Veröffentlicht in: | Nature (London) 1971-03, Vol.230 (10), p.50-52 |
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description | GEERING et al.1 reported that feline leukaemia viruses shared one of the group specific antigens of the murine leukaemia viruses, gs-3, as detected by immunoprecipitation in agar gels with broadly reactive rat antisera to the group specific antigens of the murine leukaemia viruses (MuLV). Subsequently, they found that this shared group specific antigen was also present in the hamster and rat C-type viruses2. Work by Schafer3 and our own immunodiffusion4 and complement fixation studies have confirmed the immunological reactivity between the feline leukaemia viral antigens and broad-reacting murine leukaemia group specific antisera. We have now applied this interspecies immunological reaction between the murine and feline C-type viruses to quantitative studies of the feline leukaemia viruses. Broad-reactive murine leukaemia-sarcoma group specific antisera prepared in rats by the induction of murine sarcoma virus (MSV) tumours5, 6 were found to be as useful and nearly as sensitive as a feline leukaemia-sarcoma specific, group specific antiserum for the in vitro detection and assay of the noncytopathogenic feline leukaemia virus (FeLV). |
doi_str_mv | 10.1038/newbio230050a0 |
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Subsequently, they found that this shared group specific antigen was also present in the hamster and rat C-type viruses2. Work by Schafer3 and our own immunodiffusion4 and complement fixation studies have confirmed the immunological reactivity between the feline leukaemia viral antigens and broad-reacting murine leukaemia group specific antisera. We have now applied this interspecies immunological reaction between the murine and feline C-type viruses to quantitative studies of the feline leukaemia viruses. Broad-reactive murine leukaemia-sarcoma group specific antisera prepared in rats by the induction of murine sarcoma virus (MSV) tumours5, 6 were found to be as useful and nearly as sensitive as a feline leukaemia-sarcoma specific, group specific antiserum for the in vitro detection and assay of the noncytopathogenic feline leukaemia virus (FeLV).</description><identifier>ISSN: 0028-0836</identifier><identifier>ISSN: 0090-0028</identifier><identifier>EISSN: 1476-4687</identifier><identifier>EISSN: 2058-1092</identifier><identifier>DOI: 10.1038/newbio230050a0</identifier><identifier>PMID: 5279807</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>Animals ; Antigens - analysis ; Biomedical and Life Sciences ; Cat Diseases - microbiology ; Cats ; Complement Fixation Tests ; Immune Sera ; letters-to-editor ; Leukemia - veterinary ; Life Sciences ; Mice ; Moloney murine leukemia virus - immunology ; Retroviridae - immunology</subject><ispartof>Nature (London), 1971-03, Vol.230 (10), p.50-52</ispartof><rights>Springer Nature Limited 1971</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c359t-8718b78a929c4e9dd8d4aa7a5476ab8f96e378b2f22977b5bfa4a211c94739da3</citedby><cites>FETCH-LOGICAL-c359t-8718b78a929c4e9dd8d4aa7a5476ab8f96e378b2f22977b5bfa4a211c94739da3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,2727,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/5279807$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>SARMA, PADMAN S</creatorcontrib><creatorcontrib>HUEBNER, ROBERT J</creatorcontrib><creatorcontrib>TURNER, HORACE C</creatorcontrib><creatorcontrib>GILDEN, RAYMOND V</creatorcontrib><creatorcontrib>LOG, TZE-SIUNG</creatorcontrib><title>Feline Leukaemia Viral Antigens and Antisera to the Group Specific Antigens of the Murine Leukaemia Viruses</title><title>Nature (London)</title><addtitle>Nature New Biology</addtitle><addtitle>Nat New Biol</addtitle><description>GEERING et al.1 reported that feline leukaemia viruses shared one of the group specific antigens of the murine leukaemia viruses, gs-3, as detected by immunoprecipitation in agar gels with broadly reactive rat antisera to the group specific antigens of the murine leukaemia viruses (MuLV). Subsequently, they found that this shared group specific antigen was also present in the hamster and rat C-type viruses2. Work by Schafer3 and our own immunodiffusion4 and complement fixation studies have confirmed the immunological reactivity between the feline leukaemia viral antigens and broad-reacting murine leukaemia group specific antisera. We have now applied this interspecies immunological reaction between the murine and feline C-type viruses to quantitative studies of the feline leukaemia viruses. Broad-reactive murine leukaemia-sarcoma group specific antisera prepared in rats by the induction of murine sarcoma virus (MSV) tumours5, 6 were found to be as useful and nearly as sensitive as a feline leukaemia-sarcoma specific, group specific antiserum for the in vitro detection and assay of the noncytopathogenic feline leukaemia virus (FeLV).</description><subject>Animals</subject><subject>Antigens - analysis</subject><subject>Biomedical and Life Sciences</subject><subject>Cat Diseases - microbiology</subject><subject>Cats</subject><subject>Complement Fixation Tests</subject><subject>Immune Sera</subject><subject>letters-to-editor</subject><subject>Leukemia - veterinary</subject><subject>Life Sciences</subject><subject>Mice</subject><subject>Moloney murine leukemia virus - immunology</subject><subject>Retroviridae - immunology</subject><issn>0028-0836</issn><issn>0090-0028</issn><issn>1476-4687</issn><issn>2058-1092</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1971</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kE1Lw0AQhhdRaq1evQk5iLfU3Xzt7rEUW4WKBz-uYZJM6rbJpu5mEf-9sSkVFU_D8D7zwLyEnDM6ZjQU1xrfM9UEIaUxBXpAhiziiR8lgh-SIaWB8KkIk2NyYu2KdhDj0YAM4oBLQfmQrGdYKY3eAt0asFbgvSgDlTfRrVqith7oYrtYNOC1jde-ojc3jdt4jxvMVanyb7Ypt_G9M3-UzqI9JUclVBbPdnNEnmc3T9Nbf_Ewv5tOFn4exrL1BWci4wJkIPMIZVGIIgLgEHePQSZKmWDIRRaUQSA5z-KshAgCxnIZ8VAWEI7IVe_dmObNoW3TWtkcqwo0Ns6mgspYMEk7cNyDuWmsNVimG6NqMB8po-lXu-nPdruDi53ZZTUWe3xXZ5df97ntEr1Ek64aZ3T37P_Gy_5CQ-sM7o2_sE8d_5PE</recordid><startdate>19710310</startdate><enddate>19710310</enddate><creator>SARMA, PADMAN S</creator><creator>HUEBNER, ROBERT J</creator><creator>TURNER, HORACE C</creator><creator>GILDEN, RAYMOND V</creator><creator>LOG, TZE-SIUNG</creator><general>Nature Publishing Group UK</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19710310</creationdate><title>Feline Leukaemia Viral Antigens and Antisera to the Group Specific Antigens of the Murine Leukaemia Viruses</title><author>SARMA, PADMAN S ; HUEBNER, ROBERT J ; TURNER, HORACE C ; GILDEN, RAYMOND V ; LOG, TZE-SIUNG</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c359t-8718b78a929c4e9dd8d4aa7a5476ab8f96e378b2f22977b5bfa4a211c94739da3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1971</creationdate><topic>Animals</topic><topic>Antigens - analysis</topic><topic>Biomedical and Life Sciences</topic><topic>Cat Diseases - microbiology</topic><topic>Cats</topic><topic>Complement Fixation Tests</topic><topic>Immune Sera</topic><topic>letters-to-editor</topic><topic>Leukemia - veterinary</topic><topic>Life Sciences</topic><topic>Mice</topic><topic>Moloney murine leukemia virus - immunology</topic><topic>Retroviridae - immunology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>SARMA, PADMAN S</creatorcontrib><creatorcontrib>HUEBNER, ROBERT J</creatorcontrib><creatorcontrib>TURNER, HORACE C</creatorcontrib><creatorcontrib>GILDEN, RAYMOND V</creatorcontrib><creatorcontrib>LOG, TZE-SIUNG</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Nature (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>SARMA, PADMAN S</au><au>HUEBNER, ROBERT J</au><au>TURNER, HORACE C</au><au>GILDEN, RAYMOND V</au><au>LOG, TZE-SIUNG</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Feline Leukaemia Viral Antigens and Antisera to the Group Specific Antigens of the Murine Leukaemia Viruses</atitle><jtitle>Nature (London)</jtitle><stitle>Nature New Biology</stitle><addtitle>Nat New Biol</addtitle><date>1971-03-10</date><risdate>1971</risdate><volume>230</volume><issue>10</issue><spage>50</spage><epage>52</epage><pages>50-52</pages><issn>0028-0836</issn><issn>0090-0028</issn><eissn>1476-4687</eissn><eissn>2058-1092</eissn><abstract>GEERING et al.1 reported that feline leukaemia viruses shared one of the group specific antigens of the murine leukaemia viruses, gs-3, as detected by immunoprecipitation in agar gels with broadly reactive rat antisera to the group specific antigens of the murine leukaemia viruses (MuLV). Subsequently, they found that this shared group specific antigen was also present in the hamster and rat C-type viruses2. Work by Schafer3 and our own immunodiffusion4 and complement fixation studies have confirmed the immunological reactivity between the feline leukaemia viral antigens and broad-reacting murine leukaemia group specific antisera. We have now applied this interspecies immunological reaction between the murine and feline C-type viruses to quantitative studies of the feline leukaemia viruses. Broad-reactive murine leukaemia-sarcoma group specific antisera prepared in rats by the induction of murine sarcoma virus (MSV) tumours5, 6 were found to be as useful and nearly as sensitive as a feline leukaemia-sarcoma specific, group specific antiserum for the in vitro detection and assay of the noncytopathogenic feline leukaemia virus (FeLV).</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>5279807</pmid><doi>10.1038/newbio230050a0</doi><tpages>3</tpages></addata></record> |
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subjects | Animals Antigens - analysis Biomedical and Life Sciences Cat Diseases - microbiology Cats Complement Fixation Tests Immune Sera letters-to-editor Leukemia - veterinary Life Sciences Mice Moloney murine leukemia virus - immunology Retroviridae - immunology |
title | Feline Leukaemia Viral Antigens and Antisera to the Group Specific Antigens of the Murine Leukaemia Viruses |
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