Comparison of the multivariate analysis and CADENZA systems for determination of the probability of coronary artery disease
The accuracy of 2 discriminate systems for diagnosis of coronary artery disease (CAD), multivariate analysis (MVA) and Bayesian analysis (CADENZA ®), was evaluated in 113 patients undergoing electrocardiographic stress testing and coronary angiography. MVA uses weighting factors (F values) generated...
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| Veröffentlicht in: | The American journal of cardiology 1984-02, Vol.53 (4), p.493-496 |
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| container_issue | 4 |
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| container_title | The American journal of cardiology |
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| creator | Greenberg, Paul S. Ellestad, Myrvin H. Clover, Robert C. |
| description | The accuracy of 2 discriminate systems for diagnosis of coronary artery disease (CAD), multivariate analysis (MVA) and Bayesian analysis (CADENZA
®), was evaluated in 113 patients undergoing electrocardiographic stress testing and coronary angiography. MVA uses weighting factors (F values) generated from our patient data, whereas CADENZA uses probabilities gleaned from an extensive review of the American literature. Overall accuracy was similar. MVA had a higher sensitivity for 1-vessel CAD (75 versus 33%), but CADENZA was better for determining the severity of CAD. The 2 systems provided posterior probabilities for disease that were highly correlated (r = 0.56; p < 0.001).
Both systems suggest the need for further testing based on the probability generated; herein lies their major strength. The application of such systems should help the clinician reach a diagnosis or make a decision as to management in a cost-effective manner. |
| doi_str_mv | 10.1016/0002-9149(84)90019-5 |
| format | Article |
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Both systems suggest the need for further testing based on the probability generated; herein lies their major strength. The application of such systems should help the clinician reach a diagnosis or make a decision as to management in a cost-effective manner.</description><subject>Bayes Theorem</subject><subject>Coronary Disease - diagnosis</subject><subject>Diagnosis, Computer-Assisted</subject><subject>Exercise Test</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Probability</subject><subject>Software</subject><issn>0002-9149</issn><issn>1879-1913</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1984</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMFO3DAQhi3Uim6BN6CSTxUcAnbiJPal0mqhgITKBS5cLK89UV0l8dbjRYp4eRx2RW-92J6Zf_4Zf4SccnbBGW8uGWNlobhQZ1KcK8a4KuoDsuCyVQVXvPpEFh-SL-Qr4p8ccl43h-SwqRrRNuWCvK7CsDHRYxhp6Gj6DXTY9sm_5JxJQM1o-gk95oejq-XV9a_nJcUJEwxIuxCpgwRx8KNJ_p_FJoa1Wfvep2lO2RDDaOJETcziiTqPYBCOyefO9Agn-_uIPP28flzdFvcPN3er5X1hq7pNhWyr2oDMh6uhVFyKlithpWulrErruGvK2jadLWXTViAkl1CXVpo1mJp3rjoi33e-ea2_W8CkB48W-t6MELaoJVNiHpKFYie0MSBG6PQm-iEvrjnTM3M9A9UzUC2Ffmeu57Zve__tegD30bSHnOs_dnXIn3zxEDVaD6MF5yPYpF3w_x_wBnwfkhc</recordid><startdate>19840201</startdate><enddate>19840201</enddate><creator>Greenberg, Paul S.</creator><creator>Ellestad, Myrvin H.</creator><creator>Clover, Robert C.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19840201</creationdate><title>Comparison of the multivariate analysis and CADENZA systems for determination of the probability of coronary artery disease</title><author>Greenberg, Paul S. ; Ellestad, Myrvin H. ; Clover, Robert C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c357t-8735ae835ad5e291847194c8d78832cd1d625c6fc28673e4818e52c8abea51fd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1984</creationdate><topic>Bayes Theorem</topic><topic>Coronary Disease - diagnosis</topic><topic>Diagnosis, Computer-Assisted</topic><topic>Exercise Test</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Probability</topic><topic>Software</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Greenberg, Paul S.</creatorcontrib><creatorcontrib>Ellestad, Myrvin H.</creatorcontrib><creatorcontrib>Clover, Robert C.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Greenberg, Paul S.</au><au>Ellestad, Myrvin H.</au><au>Clover, Robert C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparison of the multivariate analysis and CADENZA systems for determination of the probability of coronary artery disease</atitle><jtitle>The American journal of cardiology</jtitle><addtitle>Am J Cardiol</addtitle><date>1984-02-01</date><risdate>1984</risdate><volume>53</volume><issue>4</issue><spage>493</spage><epage>496</epage><pages>493-496</pages><issn>0002-9149</issn><eissn>1879-1913</eissn><abstract>The accuracy of 2 discriminate systems for diagnosis of coronary artery disease (CAD), multivariate analysis (MVA) and Bayesian analysis (CADENZA
®), was evaluated in 113 patients undergoing electrocardiographic stress testing and coronary angiography. MVA uses weighting factors (F values) generated from our patient data, whereas CADENZA uses probabilities gleaned from an extensive review of the American literature. Overall accuracy was similar. MVA had a higher sensitivity for 1-vessel CAD (75 versus 33%), but CADENZA was better for determining the severity of CAD. The 2 systems provided posterior probabilities for disease that were highly correlated (r = 0.56; p < 0.001).
Both systems suggest the need for further testing based on the probability generated; herein lies their major strength. The application of such systems should help the clinician reach a diagnosis or make a decision as to management in a cost-effective manner.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>6364762</pmid><doi>10.1016/0002-9149(84)90019-5</doi><tpages>4</tpages></addata></record> |
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| identifier | ISSN: 0002-9149 |
| ispartof | The American journal of cardiology, 1984-02, Vol.53 (4), p.493-496 |
| issn | 0002-9149 1879-1913 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Bayes Theorem Coronary Disease - diagnosis Diagnosis, Computer-Assisted Exercise Test Female Humans Male Middle Aged Probability Software |
| title | Comparison of the multivariate analysis and CADENZA systems for determination of the probability of coronary artery disease |
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