Neonatal Bilirubin Production Estimated from “End-Tidal” Carbon Monoxide Concentration
The relationship between the pulmonary excretion rate of carbon monoxide (VECO) and the concentration of CO, in a sample of breath, drawn through a nasopharyngeal catheter at end-expiration, was assessed in 25 studies of nine preterm and 14 term infants. The VECO and this approximate end-tidal sampl...
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| Veröffentlicht in: | Journal of pediatric gastroenterology and nutrition 1984-01, Vol.3 (1), p.77-80 |
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| container_title | Journal of pediatric gastroenterology and nutrition |
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| creator | Smith, David W Hopper, Andrew O Shahin, Susan M Cohen, Ronald S Ostrander, Clinton R Ariagno, Ronald L Stevenson, David K |
| description | The relationship between the pulmonary excretion rate of carbon monoxide (VECO) and the concentration of CO, in a sample of breath, drawn through a nasopharyngeal catheter at end-expiration, was assessed in 25 studies of nine preterm and 14 term infants. The VECO and this approximate end-tidal sample of CO (ETCO) correlated significantly over a wide range of CO elimination ratesVECO = 10.45 ETCO + 2.25 (n = 25, r = 0.95). The ETCO correctly predicted elevations in VECO > 2 SD of the mean VECO for normal infants (13.9 ± 3.5 μl/kg/h), with 90% sensitivity and 73% specificity (p < 0.01). Three subjects with Rh isoimmune hemolytic disease were easily identified by the ETCO as well as the VECO. The ETco is a simple, noninvasive measurement for rapidly identifying infants with significant hemolytic disease. |
| doi_str_mv | 10.1097/00005176-198401000-00017 |
| format | Article |
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The VECO and this approximate end-tidal sample of CO (ETCO) correlated significantly over a wide range of CO elimination ratesVECO = 10.45 ETCO + 2.25 (n = 25, r = 0.95). The ETCO correctly predicted elevations in VECO > 2 SD of the mean VECO for normal infants (13.9 ± 3.5 μl/kg/h), with 90% sensitivity and 73% specificity (p < 0.01). Three subjects with Rh isoimmune hemolytic disease were easily identified by the ETCO as well as the VECO. The ETco is a simple, noninvasive measurement for rapidly identifying infants with significant hemolytic disease.</description><identifier>ISSN: 0277-2116</identifier><identifier>EISSN: 1536-4801</identifier><identifier>DOI: 10.1097/00005176-198401000-00017</identifier><identifier>PMID: 6537974</identifier><identifier>CODEN: JPGND6</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott-Raven Publishers</publisher><subject>Bilirubin - biosynthesis ; Biological and medical sciences ; Breath Tests ; Carbon Monoxide - analysis ; Carboxyhemoglobin - analysis ; Erythroblastosis, Fetal - diagnosis ; Female ; Fundamental and applied biological sciences. Psychology ; Humans ; Infant, Newborn ; Infant, Premature ; Liver. Bile. Biliary tracts ; Pregnancy ; Vertebrates: digestive system</subject><ispartof>Journal of pediatric gastroenterology and nutrition, 1984-01, Vol.3 (1), p.77-80</ispartof><rights>Lippincott-Raven Publishers.</rights><rights>1984 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5007-a1ff44235974654f27ebe7afdc540970b3e274da308d1fd948441f93863cd0913</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,4024,27923,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=9575369$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6537974$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Smith, David W</creatorcontrib><creatorcontrib>Hopper, Andrew O</creatorcontrib><creatorcontrib>Shahin, Susan M</creatorcontrib><creatorcontrib>Cohen, Ronald S</creatorcontrib><creatorcontrib>Ostrander, Clinton R</creatorcontrib><creatorcontrib>Ariagno, Ronald L</creatorcontrib><creatorcontrib>Stevenson, David K</creatorcontrib><title>Neonatal Bilirubin Production Estimated from “End-Tidal” Carbon Monoxide Concentration</title><title>Journal of pediatric gastroenterology and nutrition</title><addtitle>J Pediatr Gastroenterol Nutr</addtitle><description>The relationship between the pulmonary excretion rate of carbon monoxide (VECO) and the concentration of CO, in a sample of breath, drawn through a nasopharyngeal catheter at end-expiration, was assessed in 25 studies of nine preterm and 14 term infants. The VECO and this approximate end-tidal sample of CO (ETCO) correlated significantly over a wide range of CO elimination ratesVECO = 10.45 ETCO + 2.25 (n = 25, r = 0.95). The ETCO correctly predicted elevations in VECO > 2 SD of the mean VECO for normal infants (13.9 ± 3.5 μl/kg/h), with 90% sensitivity and 73% specificity (p < 0.01). Three subjects with Rh isoimmune hemolytic disease were easily identified by the ETCO as well as the VECO. The ETco is a simple, noninvasive measurement for rapidly identifying infants with significant hemolytic disease.</description><subject>Bilirubin - biosynthesis</subject><subject>Biological and medical sciences</subject><subject>Breath Tests</subject><subject>Carbon Monoxide - analysis</subject><subject>Carboxyhemoglobin - analysis</subject><subject>Erythroblastosis, Fetal - diagnosis</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Infant, Premature</subject><subject>Liver. Bile. Biliary tracts</subject><subject>Pregnancy</subject><subject>Vertebrates: digestive system</subject><issn>0277-2116</issn><issn>1536-4801</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1984</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kc9OGzEQxq0KlAbaR0DaQ8Vtqb221-tjidKClNIe4NKL5fUfxeDY1N5V6I0HgZfLk2BImhuWRtZofp898w0AFYJnCHL2FZZDEWtrxDsCUcnqEoh9AFNEcVuTDqIDMIUNY3WDUPsRHOV8WxBGKJyASUsx44xMwZ8rE4McpK_OnXdp7F2ofqeoRzW4GKp5HtxKDkZXNsVVtXl8mgddXzst_ebxuZrJ1BfqZwzxwWlTzWJQJgxJvoo_gUMrfTafd_cxuPk-v55d1ItfPy5n3xa1oqWfWiJrCWkwLf20lNiGmd4wabWipIwKe2waRrTEsNPIak46QpDluGux0pAjfAxOt-_ep_h3NHkQK5eV8V4GE8csOsgJ5R0uYLcFVYo5J2PFfSrTpX8CQfFqq_hvq9jbKt5sLdKT3R9jvzJ6L9z5WOpfdnWZlfQ2yaBc3mOcsrIVXjCyxdbRDyblOz-uTRJLI_2wFO8tFb8AJEaQaA</recordid><startdate>198401</startdate><enddate>198401</enddate><creator>Smith, David W</creator><creator>Hopper, Andrew O</creator><creator>Shahin, Susan M</creator><creator>Cohen, Ronald S</creator><creator>Ostrander, Clinton R</creator><creator>Ariagno, Ronald L</creator><creator>Stevenson, David K</creator><general>Lippincott-Raven Publishers</general><general>Lippincott</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198401</creationdate><title>Neonatal Bilirubin Production Estimated from “End-Tidal” Carbon Monoxide Concentration</title><author>Smith, David W ; Hopper, Andrew O ; Shahin, Susan M ; Cohen, Ronald S ; Ostrander, Clinton R ; Ariagno, Ronald L ; Stevenson, David K</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5007-a1ff44235974654f27ebe7afdc540970b3e274da308d1fd948441f93863cd0913</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1984</creationdate><topic>Bilirubin - biosynthesis</topic><topic>Biological and medical sciences</topic><topic>Breath Tests</topic><topic>Carbon Monoxide - analysis</topic><topic>Carboxyhemoglobin - analysis</topic><topic>Erythroblastosis, Fetal - diagnosis</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Infant, Premature</topic><topic>Liver. Bile. Biliary tracts</topic><topic>Pregnancy</topic><topic>Vertebrates: digestive system</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Smith, David W</creatorcontrib><creatorcontrib>Hopper, Andrew O</creatorcontrib><creatorcontrib>Shahin, Susan M</creatorcontrib><creatorcontrib>Cohen, Ronald S</creatorcontrib><creatorcontrib>Ostrander, Clinton R</creatorcontrib><creatorcontrib>Ariagno, Ronald L</creatorcontrib><creatorcontrib>Stevenson, David K</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of pediatric gastroenterology and nutrition</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Smith, David W</au><au>Hopper, Andrew O</au><au>Shahin, Susan M</au><au>Cohen, Ronald S</au><au>Ostrander, Clinton R</au><au>Ariagno, Ronald L</au><au>Stevenson, David K</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Neonatal Bilirubin Production Estimated from “End-Tidal” Carbon Monoxide Concentration</atitle><jtitle>Journal of pediatric gastroenterology and nutrition</jtitle><addtitle>J Pediatr Gastroenterol Nutr</addtitle><date>1984-01</date><risdate>1984</risdate><volume>3</volume><issue>1</issue><spage>77</spage><epage>80</epage><pages>77-80</pages><issn>0277-2116</issn><eissn>1536-4801</eissn><coden>JPGND6</coden><abstract>The relationship between the pulmonary excretion rate of carbon monoxide (VECO) and the concentration of CO, in a sample of breath, drawn through a nasopharyngeal catheter at end-expiration, was assessed in 25 studies of nine preterm and 14 term infants. The VECO and this approximate end-tidal sample of CO (ETCO) correlated significantly over a wide range of CO elimination ratesVECO = 10.45 ETCO + 2.25 (n = 25, r = 0.95). The ETCO correctly predicted elevations in VECO > 2 SD of the mean VECO for normal infants (13.9 ± 3.5 μl/kg/h), with 90% sensitivity and 73% specificity (p < 0.01). Three subjects with Rh isoimmune hemolytic disease were easily identified by the ETCO as well as the VECO. The ETco is a simple, noninvasive measurement for rapidly identifying infants with significant hemolytic disease.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott-Raven Publishers</pub><pmid>6537974</pmid><doi>10.1097/00005176-198401000-00017</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 0277-2116 |
| ispartof | Journal of pediatric gastroenterology and nutrition, 1984-01, Vol.3 (1), p.77-80 |
| issn | 0277-2116 1536-4801 |
| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Bilirubin - biosynthesis Biological and medical sciences Breath Tests Carbon Monoxide - analysis Carboxyhemoglobin - analysis Erythroblastosis, Fetal - diagnosis Female Fundamental and applied biological sciences. Psychology Humans Infant, Newborn Infant, Premature Liver. Bile. Biliary tracts Pregnancy Vertebrates: digestive system |
| title | Neonatal Bilirubin Production Estimated from “End-Tidal” Carbon Monoxide Concentration |
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