Binding of Sheep Red Blood Cells to a Large Population of Human Lymphocytes
WHILE investigating the interaction between antigen–antibody–complement complexes and lymphoid cells 1 , we have noticed that sheep red blood cells (SRBC) adhered to a surprisingly large proportion of human peripheral blood lymphocytes forming clusters (“rosettes”). We have now examined the conditio...
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| Veröffentlicht in: | Nature (London) 1971-04, Vol.230 (5295), p.531-532 |
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| container_end_page | 532 |
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| container_issue | 5295 |
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| container_title | Nature (London) |
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| creator | LAY, WALTRAUT H MENDES, NELSON F BIANCO, CELSO NUSSENZWEIG, VICTOR |
| description | WHILE investigating the interaction between antigen–antibody–complement complexes and lymphoid cells
1
, we have noticed that sheep red blood cells (SRBC) adhered to a surprisingly large proportion of human peripheral blood lymphocytes forming clusters (“rosettes”). We have now examined the conditions in which this interaction occurs, and the frequency of rosette forming lymphocytes in the peripheral blood of normal individuals and a few patients with haematological diseases. |
| doi_str_mv | 10.1038/230531a0 |
| format | Article |
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, we have noticed that sheep red blood cells (SRBC) adhered to a surprisingly large proportion of human peripheral blood lymphocytes forming clusters (“rosettes”). We have now examined the conditions in which this interaction occurs, and the frequency of rosette forming lymphocytes in the peripheral blood of normal individuals and a few patients with haematological diseases.</description><identifier>ISSN: 0028-0836</identifier><identifier>EISSN: 1476-4687</identifier><identifier>DOI: 10.1038/230531a0</identifier><identifier>PMID: 4927757</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>Animals ; Cell Adhesion ; Erythrocytes - cytology ; Hodgkin Disease - blood ; Humanities and Social Sciences ; Humans ; In Vitro Techniques ; letter ; Leukemia, Lymphoid - blood ; Lymphocytes - cytology ; Lymphoma, Non-Hodgkin - blood ; multidisciplinary ; Science ; Science (multidisciplinary) ; Sheep</subject><ispartof>Nature (London), 1971-04, Vol.230 (5295), p.531-532</ispartof><rights>Springer Nature Limited 1971</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c335t-bcc04f542b2533c80e09dcc05d98e19d5036520bc1d66f110a91e96ae8370943</citedby><cites>FETCH-LOGICAL-c335t-bcc04f542b2533c80e09dcc05d98e19d5036520bc1d66f110a91e96ae8370943</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,2727,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4927757$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>LAY, WALTRAUT H</creatorcontrib><creatorcontrib>MENDES, NELSON F</creatorcontrib><creatorcontrib>BIANCO, CELSO</creatorcontrib><creatorcontrib>NUSSENZWEIG, VICTOR</creatorcontrib><title>Binding of Sheep Red Blood Cells to a Large Population of Human Lymphocytes</title><title>Nature (London)</title><addtitle>Nature</addtitle><addtitle>Nature</addtitle><description>WHILE investigating the interaction between antigen–antibody–complement complexes and lymphoid cells
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, we have noticed that sheep red blood cells (SRBC) adhered to a surprisingly large proportion of human peripheral blood lymphocytes forming clusters (“rosettes”). We have now examined the conditions in which this interaction occurs, and the frequency of rosette forming lymphocytes in the peripheral blood of normal individuals and a few patients with haematological diseases.</description><subject>Animals</subject><subject>Cell Adhesion</subject><subject>Erythrocytes - cytology</subject><subject>Hodgkin Disease - blood</subject><subject>Humanities and Social Sciences</subject><subject>Humans</subject><subject>In Vitro Techniques</subject><subject>letter</subject><subject>Leukemia, Lymphoid - blood</subject><subject>Lymphocytes - cytology</subject><subject>Lymphoma, Non-Hodgkin - blood</subject><subject>multidisciplinary</subject><subject>Science</subject><subject>Science (multidisciplinary)</subject><subject>Sheep</subject><issn>0028-0836</issn><issn>1476-4687</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1971</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkE1Pg0AQhjdGU2s18Q9o9mT0gM6yLCxH2_gVSTTaO1nYoaUBFnfh0H8vDbUnT5PM--TJzEvIJYN7Blw--BwEZwqOyJQFUegFoYyOyRTAlx5IHp6SM-c2ACBYFEzIJIj9KBLRlLzPy0aXzYqagn6vEVv6hZrOK2M0XWBVOdoZqmii7Arpp2n7SnWlaXb4a1-rhibbul2bfNuhOycnhaocXuznjCyfn5aLVy_5eHlbPCZezrnovCzPIShE4Ge-4DyXgBDrYSd0LJHFWgAPhQ9ZznQYFoyBihnGoULJI4gDPiM3o7a15qdH16V16fLhVtWg6V0qdxBj_gDejmBujXMWi7S1Za3sNmWQ7mpL_2ob0Ku9s89q1Adw39OQ3425G5JmhTbdmN42w5f_ua5HtlFdb_HgOgC_sTp8Xw</recordid><startdate>19710423</startdate><enddate>19710423</enddate><creator>LAY, WALTRAUT H</creator><creator>MENDES, NELSON F</creator><creator>BIANCO, CELSO</creator><creator>NUSSENZWEIG, VICTOR</creator><general>Nature Publishing Group UK</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19710423</creationdate><title>Binding of Sheep Red Blood Cells to a Large Population of Human Lymphocytes</title><author>LAY, WALTRAUT H ; MENDES, NELSON F ; BIANCO, CELSO ; NUSSENZWEIG, VICTOR</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c335t-bcc04f542b2533c80e09dcc05d98e19d5036520bc1d66f110a91e96ae8370943</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1971</creationdate><topic>Animals</topic><topic>Cell Adhesion</topic><topic>Erythrocytes - cytology</topic><topic>Hodgkin Disease - blood</topic><topic>Humanities and Social Sciences</topic><topic>Humans</topic><topic>In Vitro Techniques</topic><topic>letter</topic><topic>Leukemia, Lymphoid - blood</topic><topic>Lymphocytes - cytology</topic><topic>Lymphoma, Non-Hodgkin - blood</topic><topic>multidisciplinary</topic><topic>Science</topic><topic>Science (multidisciplinary)</topic><topic>Sheep</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>LAY, WALTRAUT H</creatorcontrib><creatorcontrib>MENDES, NELSON F</creatorcontrib><creatorcontrib>BIANCO, CELSO</creatorcontrib><creatorcontrib>NUSSENZWEIG, VICTOR</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Nature (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>LAY, WALTRAUT H</au><au>MENDES, NELSON F</au><au>BIANCO, CELSO</au><au>NUSSENZWEIG, VICTOR</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Binding of Sheep Red Blood Cells to a Large Population of Human Lymphocytes</atitle><jtitle>Nature (London)</jtitle><stitle>Nature</stitle><addtitle>Nature</addtitle><date>1971-04-23</date><risdate>1971</risdate><volume>230</volume><issue>5295</issue><spage>531</spage><epage>532</epage><pages>531-532</pages><issn>0028-0836</issn><eissn>1476-4687</eissn><abstract>WHILE investigating the interaction between antigen–antibody–complement complexes and lymphoid cells
1
, we have noticed that sheep red blood cells (SRBC) adhered to a surprisingly large proportion of human peripheral blood lymphocytes forming clusters (“rosettes”). We have now examined the conditions in which this interaction occurs, and the frequency of rosette forming lymphocytes in the peripheral blood of normal individuals and a few patients with haematological diseases.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>4927757</pmid><doi>10.1038/230531a0</doi><tpages>2</tpages></addata></record> |
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| ispartof | Nature (London), 1971-04, Vol.230 (5295), p.531-532 |
| issn | 0028-0836 1476-4687 |
| language | eng |
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| source | MEDLINE; Nature; Alma/SFX Local Collection |
| subjects | Animals Cell Adhesion Erythrocytes - cytology Hodgkin Disease - blood Humanities and Social Sciences Humans In Vitro Techniques letter Leukemia, Lymphoid - blood Lymphocytes - cytology Lymphoma, Non-Hodgkin - blood multidisciplinary Science Science (multidisciplinary) Sheep |
| title | Binding of Sheep Red Blood Cells to a Large Population of Human Lymphocytes |
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