Allergic bronchopulmonary aspergillosis in cystic fibrosis

One hundred patients with CF were screened for ABPA. Forty-eight male patients and 52 female patients with an age range of 2 to 34 yr (mean 14.2) were studied. Patients were evaluated for skin reactivity and serum precipitating antibodies to Af, predominant sputum organisms, total blood eosinophil l...

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Veröffentlicht in:Journal of allergy and clinical immunology 1984, Vol.73 (1), p.44-48
Hauptverfasser: Laufer, Peter, Fink, Jordan N., Bruns, W.Theodore, Unger, George F., Kalbfleisch, John H., Greenberger, Paul A., Patterson, Roy
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container_end_page 48
container_issue 1
container_start_page 44
container_title Journal of allergy and clinical immunology
container_volume 73
creator Laufer, Peter
Fink, Jordan N.
Bruns, W.Theodore
Unger, George F.
Kalbfleisch, John H.
Greenberger, Paul A.
Patterson, Roy
description One hundred patients with CF were screened for ABPA. Forty-eight male patients and 52 female patients with an age range of 2 to 34 yr (mean 14.2) were studied. Patients were evaluated for skin reactivity and serum precipitating antibodies to Af, predominant sputum organisms, total blood eosinophil levels, total serum IgE, and Af-specific IgE and IgG, as well as abnormalities of pulmonary function and chest x-ray films. Careful evaluation of all patients with CF demonstrated that 10% had features indicative of ABPA, which is another potentially destructive pulmonary disorder. Thus careful evaluation of patients with CF, especially those with asthma, may be rewarding in uncovering a disorder that may slow progression of CF when it is appropriately treated.
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subjects Adolescent
Adult
Aspergillosis, Allergic Bronchopulmonary - complications
Aspergillosis, Allergic Bronchopulmonary - diagnosis
Aspergillus
Asthma - complications
Asthma - diagnosis
Biological and medical sciences
Child
Child, Preschool
Cystic Fibrosis - complications
Cystic Fibrosis - diagnosis
Female
Gastroenterology. Liver. Pancreas. Abdomen
Humans
Liver. Biliary tract. Portal circulation. Exocrine pancreas
Male
Medical sciences
Other diseases. Semiology
Sputum - microbiology
title Allergic bronchopulmonary aspergillosis in cystic fibrosis
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