Effect of penicillin prophylaxis on nasopharyngeal colonization with Streptococcus pneumoniae in children with sickle cell anemia

Polyavalent pneumococcal vaccine and oral penicillin prophylaxis are frequently used in patients with functional or anatomic asplenia to protect them from fulminant Streptococcus pneumoniae sepsis. We studied nasopharyngeal colonization with pneumococci in 34 patients with sickle cell anemia (aged 6...

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Veröffentlicht in:	The Journal of pediatrics 1984, Vol.104 (1), p.18-22
Hauptverfasser:	Anglin, David L., Siegel, Jane D., Pacini, David L., Smith, Susan J., Adams, Greg, Buchanan, George R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anemia, Sickle Cell - complications Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Biological and medical sciences Child, Preschool Hematologic and hematopoietic diseases Humans Infant Medical sciences Other diseases. Hematologic involvement in other diseases Patient Compliance Penicillin Resistance Penicillins - therapeutic use Pharmacology. Drug treatments Pneumococcal Infections - prevention & control Prevention and actions Public health. Hygiene Public health. Hygiene-occupational medicine Sepsis - prevention & control Serotyping Specific populations (family, woman, child, elderly...) Streptococcus pneumoniae - drug effects Streptococcus pneumoniae - isolation & purification Tropical medicine
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