Levels of uric acid in the intestinal tracts of germfree, gnotobiotic, and conventional mice
The levels of uric acid in various segments of the intestinal tract of germfree, monoassociated, polyassociated, and conventional mice was determined by an enzymatic, spectrophotometric procedure. The amount of uric acid in the intestinal lumen of all mice was found to decrease as the content moved...
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Veröffentlicht in: | Metabolism, clinical and experimental clinical and experimental, 1971-03, Vol.20 (3), p.278-279 |
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description | The levels of uric acid in various segments of the intestinal tract of germfree, monoassociated, polyassociated, and conventional mice was determined by an enzymatic, spectrophotometric procedure. The amount of uric acid in the intestinal lumen of all mice was found to decrease as the content moved down the tract. Although uric acid was detected in the distal portions of the tracts of germfree mice, none was found in the cecum or large intestine of mice that were associated with bacteria. |
doi_str_mv | 10.1016/0026-0495(71)90111-9 |
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The amount of uric acid in the intestinal lumen of all mice was found to decrease as the content moved down the tract. Although uric acid was detected in the distal portions of the tracts of germfree mice, none was found in the cecum or large intestine of mice that were associated with bacteria.</description><identifier>ISSN: 0026-0495</identifier><identifier>EISSN: 1532-8600</identifier><identifier>DOI: 10.1016/0026-0495(71)90111-9</identifier><identifier>PMID: 5546924</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Animals ; Cecum - analysis ; Enterobacter - metabolism ; Germ-Free Life ; Intestinal Mucosa - metabolism ; Intestine, Large - analysis ; Intestine, Small - analysis ; Mice ; Spectrophotometry ; Uric Acid - analysis ; Uric Acid - metabolism</subject><ispartof>Metabolism, clinical and experimental, 1971-03, Vol.20 (3), p.278-279</ispartof><rights>1971</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c357t-5d4ea53b99a91011251e6a9c6b7529d097bc5cdec61822c49b4e742f0d09eb2e3</citedby><cites>FETCH-LOGICAL-c357t-5d4ea53b99a91011251e6a9c6b7529d097bc5cdec61822c49b4e742f0d09eb2e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0026-0495(71)90111-9$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>315,781,785,3551,27926,27927,45997</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/5546924$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cole, John S.</creatorcontrib><creatorcontrib>Wiseman, Ralph F.</creatorcontrib><title>Levels of uric acid in the intestinal tracts of germfree, gnotobiotic, and conventional mice</title><title>Metabolism, clinical and experimental</title><addtitle>Metabolism</addtitle><description>The levels of uric acid in various segments of the intestinal tract of germfree, monoassociated, polyassociated, and conventional mice was determined by an enzymatic, spectrophotometric procedure. The amount of uric acid in the intestinal lumen of all mice was found to decrease as the content moved down the tract. Although uric acid was detected in the distal portions of the tracts of germfree mice, none was found in the cecum or large intestine of mice that were associated with bacteria.</description><subject>Animals</subject><subject>Cecum - analysis</subject><subject>Enterobacter - metabolism</subject><subject>Germ-Free Life</subject><subject>Intestinal Mucosa - metabolism</subject><subject>Intestine, Large - analysis</subject><subject>Intestine, Small - analysis</subject><subject>Mice</subject><subject>Spectrophotometry</subject><subject>Uric Acid - analysis</subject><subject>Uric Acid - metabolism</subject><issn>0026-0495</issn><issn>1532-8600</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1971</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1LxDAQhoMouq7-A4WcRMFqkk3a5iKI-AULXvQmhHQ61UjbrEm64L-36y579DSH92NmHkJOOLvijOfXjIk8Y1Kr84JfaMY5z_QOmXA1E1mZM7ZLJlvLATmM8YsxVhRlvk_2lZK5FnJC3ue4xDZS39AhOKAWXE1dT9MnjiNhTK63LU3BQvpzfWDomoB4ST96n3zlfHJwSW1fU_D9Evvk_CrROcAjstfYNuLxZk7J28P9691TNn95fL67nWcwU0XKVC3RqlmltdXjZ1wojrnVkFeFErpmuqhAQY2Q81IIkLqSWEjRsFHCSuBsSs7WvYvgv4fxZtO5CNi2tkc_RFMyzbVU5WiUayMEH2PAxiyC62z4MZyZFVSzImZWxEzBzR9Uo8fY6aZ_qDqst6ENxVG_WesjSVw6DCaCwx6wdgEhmdq7_xf8Atihhho</recordid><startdate>197103</startdate><enddate>197103</enddate><creator>Cole, John S.</creator><creator>Wiseman, Ralph F.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>197103</creationdate><title>Levels of uric acid in the intestinal tracts of germfree, gnotobiotic, and conventional mice</title><author>Cole, John S. ; Wiseman, Ralph F.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c357t-5d4ea53b99a91011251e6a9c6b7529d097bc5cdec61822c49b4e742f0d09eb2e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1971</creationdate><topic>Animals</topic><topic>Cecum - analysis</topic><topic>Enterobacter - metabolism</topic><topic>Germ-Free Life</topic><topic>Intestinal Mucosa - metabolism</topic><topic>Intestine, Large - analysis</topic><topic>Intestine, Small - analysis</topic><topic>Mice</topic><topic>Spectrophotometry</topic><topic>Uric Acid - analysis</topic><topic>Uric Acid - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cole, John S.</creatorcontrib><creatorcontrib>Wiseman, Ralph F.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Metabolism, clinical and experimental</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cole, John S.</au><au>Wiseman, Ralph F.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Levels of uric acid in the intestinal tracts of germfree, gnotobiotic, and conventional mice</atitle><jtitle>Metabolism, clinical and experimental</jtitle><addtitle>Metabolism</addtitle><date>1971-03</date><risdate>1971</risdate><volume>20</volume><issue>3</issue><spage>278</spage><epage>279</epage><pages>278-279</pages><issn>0026-0495</issn><eissn>1532-8600</eissn><abstract>The levels of uric acid in various segments of the intestinal tract of germfree, monoassociated, polyassociated, and conventional mice was determined by an enzymatic, spectrophotometric procedure. The amount of uric acid in the intestinal lumen of all mice was found to decrease as the content moved down the tract. Although uric acid was detected in the distal portions of the tracts of germfree mice, none was found in the cecum or large intestine of mice that were associated with bacteria.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>5546924</pmid><doi>10.1016/0026-0495(71)90111-9</doi><tpages>2</tpages></addata></record> |
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subjects | Animals Cecum - analysis Enterobacter - metabolism Germ-Free Life Intestinal Mucosa - metabolism Intestine, Large - analysis Intestine, Small - analysis Mice Spectrophotometry Uric Acid - analysis Uric Acid - metabolism |
title | Levels of uric acid in the intestinal tracts of germfree, gnotobiotic, and conventional mice |
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