Semi-quantitative paper electrophoresis of serum lipoproteins
1. The needs of epidemiologic teams and clinical investigators are served better by quantitative data in digital form than by qualitative descriptions of serum lipoprotein patterns. 2. A collaborative study of 71 normal and abnormal sera revealed that values for the principal lipoprotein fractions o...
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| Veröffentlicht in: | Clinical biochemistry 1970-01, Vol.3 (2), p.115-123 |
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| container_title | Clinical biochemistry |
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| creator | Hatch, F.T. Mazrimas, J.A. Moore, J.L. Lindgren, F.T. Jensen, L.C. Wills, R.D. Adamson, G.L. |
| description | 1.
The needs of epidemiologic teams and clinical investigators are served better by quantitative data in digital form than by qualitative descriptions of serum lipoprotein patterns.
2.
A collaborative study of 71 normal and abnormal sera revealed that values for the principal lipoprotein fractions obtained with the analytical ultracentrifuge could be estimated in from 83 to over 90 percent of samples within plus or minus 30 percent by paper electrophoresis with densitometric scanning of the strips.
3.
Since significant clinical lipoprotein disorders and the results of successful therapy involve larger changes, this degree of accuracy justifies the usage of lipoprotein electrophoresis as a semi-quantitative method. |
| doi_str_mv | 10.1016/S0009-9120(70)80016-9 |
| format | Article |
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The needs of epidemiologic teams and clinical investigators are served better by quantitative data in digital form than by qualitative descriptions of serum lipoprotein patterns.
2.
A collaborative study of 71 normal and abnormal sera revealed that values for the principal lipoprotein fractions obtained with the analytical ultracentrifuge could be estimated in from 83 to over 90 percent of samples within plus or minus 30 percent by paper electrophoresis with densitometric scanning of the strips.
3.
Since significant clinical lipoprotein disorders and the results of successful therapy involve larger changes, this degree of accuracy justifies the usage of lipoprotein electrophoresis as a semi-quantitative method.</description><identifier>ISSN: 0009-9120</identifier><identifier>EISSN: 1873-2933</identifier><identifier>DOI: 10.1016/S0009-9120(70)80016-9</identifier><identifier>PMID: 4110626</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adult ; Aged ; Blood Protein Disorders - blood ; Blood Proteins - isolation & purification ; Cholesterol - blood ; Densitometry ; Electrophoresis ; Electrophoresis, Paper ; Evaluation Studies as Topic ; Female ; Humans ; Lipoproteins - blood ; Lipoproteins - isolation & purification ; Male ; Methods ; Middle Aged ; Sex Factors ; Staining and Labeling ; Triglycerides - blood ; Ultracentrifugation</subject><ispartof>Clinical biochemistry, 1970-01, Vol.3 (2), p.115-123</ispartof><rights>1970</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c308t-38943a3efbc2cb5e13ca3b269bd891e8f989d6a58a46b024fcd5962435b332ff3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0009-9120(70)80016-9$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>315,782,786,3552,27931,27932,46002</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4110626$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hatch, F.T.</creatorcontrib><creatorcontrib>Mazrimas, J.A.</creatorcontrib><creatorcontrib>Moore, J.L.</creatorcontrib><creatorcontrib>Lindgren, F.T.</creatorcontrib><creatorcontrib>Jensen, L.C.</creatorcontrib><creatorcontrib>Wills, R.D.</creatorcontrib><creatorcontrib>Adamson, G.L.</creatorcontrib><title>Semi-quantitative paper electrophoresis of serum lipoproteins</title><title>Clinical biochemistry</title><addtitle>Clin Biochem</addtitle><description>1.
The needs of epidemiologic teams and clinical investigators are served better by quantitative data in digital form than by qualitative descriptions of serum lipoprotein patterns.
2.
A collaborative study of 71 normal and abnormal sera revealed that values for the principal lipoprotein fractions obtained with the analytical ultracentrifuge could be estimated in from 83 to over 90 percent of samples within plus or minus 30 percent by paper electrophoresis with densitometric scanning of the strips.
3.
Since significant clinical lipoprotein disorders and the results of successful therapy involve larger changes, this degree of accuracy justifies the usage of lipoprotein electrophoresis as a semi-quantitative method.</description><subject>Adult</subject><subject>Aged</subject><subject>Blood Protein Disorders - blood</subject><subject>Blood Proteins - isolation & purification</subject><subject>Cholesterol - blood</subject><subject>Densitometry</subject><subject>Electrophoresis</subject><subject>Electrophoresis, Paper</subject><subject>Evaluation Studies as Topic</subject><subject>Female</subject><subject>Humans</subject><subject>Lipoproteins - blood</subject><subject>Lipoproteins - isolation & purification</subject><subject>Male</subject><subject>Methods</subject><subject>Middle Aged</subject><subject>Sex Factors</subject><subject>Staining and Labeling</subject><subject>Triglycerides - blood</subject><subject>Ultracentrifugation</subject><issn>0009-9120</issn><issn>1873-2933</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1970</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1LAzEQhoMotVZ_QmFPoofVfOymyUFEil9Q8FA9h2x2gpHdZpvsFvz3ph_06mmYmXfmnXkQmhJ8RzDh90uMscwlofhmhm8FTrVcnqAxETOWU8nYKRofJefoIsaflNJC8BEaFYRgTvkYPSyhdfl60Kve9bp3G8g63UHIoAHTB999-wDRxczbLEIY2qxxne-C78Gt4iU6s7qJcHWIE_T18vw5f8sXH6_v86dFbhgWfc6ELJhmYCtDTVUCYUazinJZ1UISEFYKWXNdCl3wKp1oTV1KTgtWVoxRa9kEXe_3JuP1ALFXrYsGmkavwA9RCSwxSVZJWO6FJvgYA1jVBdfq8KsIVltsaodNbZmoGVY7bEqmuenBYKhaqI9TB06p_7jvQ_py4yCoaBysDNQuJE6q9u4fhz_qjn0M</recordid><startdate>19700101</startdate><enddate>19700101</enddate><creator>Hatch, F.T.</creator><creator>Mazrimas, J.A.</creator><creator>Moore, J.L.</creator><creator>Lindgren, F.T.</creator><creator>Jensen, L.C.</creator><creator>Wills, R.D.</creator><creator>Adamson, G.L.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19700101</creationdate><title>Semi-quantitative paper electrophoresis of serum lipoproteins</title><author>Hatch, F.T. ; Mazrimas, J.A. ; Moore, J.L. ; Lindgren, F.T. ; Jensen, L.C. ; Wills, R.D. ; Adamson, G.L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c308t-38943a3efbc2cb5e13ca3b269bd891e8f989d6a58a46b024fcd5962435b332ff3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1970</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Blood Protein Disorders - blood</topic><topic>Blood Proteins - isolation & purification</topic><topic>Cholesterol - blood</topic><topic>Densitometry</topic><topic>Electrophoresis</topic><topic>Electrophoresis, Paper</topic><topic>Evaluation Studies as Topic</topic><topic>Female</topic><topic>Humans</topic><topic>Lipoproteins - blood</topic><topic>Lipoproteins - isolation & purification</topic><topic>Male</topic><topic>Methods</topic><topic>Middle Aged</topic><topic>Sex Factors</topic><topic>Staining and Labeling</topic><topic>Triglycerides - blood</topic><topic>Ultracentrifugation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hatch, F.T.</creatorcontrib><creatorcontrib>Mazrimas, J.A.</creatorcontrib><creatorcontrib>Moore, J.L.</creatorcontrib><creatorcontrib>Lindgren, F.T.</creatorcontrib><creatorcontrib>Jensen, L.C.</creatorcontrib><creatorcontrib>Wills, R.D.</creatorcontrib><creatorcontrib>Adamson, G.L.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical biochemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hatch, F.T.</au><au>Mazrimas, J.A.</au><au>Moore, J.L.</au><au>Lindgren, F.T.</au><au>Jensen, L.C.</au><au>Wills, R.D.</au><au>Adamson, G.L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Semi-quantitative paper electrophoresis of serum lipoproteins</atitle><jtitle>Clinical biochemistry</jtitle><addtitle>Clin Biochem</addtitle><date>1970-01-01</date><risdate>1970</risdate><volume>3</volume><issue>2</issue><spage>115</spage><epage>123</epage><pages>115-123</pages><issn>0009-9120</issn><eissn>1873-2933</eissn><abstract>1.
The needs of epidemiologic teams and clinical investigators are served better by quantitative data in digital form than by qualitative descriptions of serum lipoprotein patterns.
2.
A collaborative study of 71 normal and abnormal sera revealed that values for the principal lipoprotein fractions obtained with the analytical ultracentrifuge could be estimated in from 83 to over 90 percent of samples within plus or minus 30 percent by paper electrophoresis with densitometric scanning of the strips.
3.
Since significant clinical lipoprotein disorders and the results of successful therapy involve larger changes, this degree of accuracy justifies the usage of lipoprotein electrophoresis as a semi-quantitative method.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>4110626</pmid><doi>10.1016/S0009-9120(70)80016-9</doi><tpages>9</tpages></addata></record> |
| fulltext | fulltext |
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| ispartof | Clinical biochemistry, 1970-01, Vol.3 (2), p.115-123 |
| issn | 0009-9120 1873-2933 |
| language | eng |
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| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Adult Aged Blood Protein Disorders - blood Blood Proteins - isolation & purification Cholesterol - blood Densitometry Electrophoresis Electrophoresis, Paper Evaluation Studies as Topic Female Humans Lipoproteins - blood Lipoproteins - isolation & purification Male Methods Middle Aged Sex Factors Staining and Labeling Triglycerides - blood Ultracentrifugation |
| title | Semi-quantitative paper electrophoresis of serum lipoproteins |
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