Modern concepts of obesity

Recent advances in the classification, etiology, treatment, and theoretical approaches to obesity are reviewed. Human and animal studies are summarized, as they relate to these categories of obesity research. Special attention is given to the possible multiple etiologies of obesity and the roles of...

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Veröffentlicht in:Nutrition reviews 1983-12, Vol.41 (12), p.361-373
Hauptverfasser: Vasselli, Joseph R, Cleary, Margot P, Van Itallie, Theodore B
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Sprache:eng
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container_end_page 373
container_issue 12
container_start_page 361
container_title Nutrition reviews
container_volume 41
creator Vasselli, Joseph R
Cleary, Margot P
Van Itallie, Theodore B
description Recent advances in the classification, etiology, treatment, and theoretical approaches to obesity are reviewed. Human and animal studies are summarized, as they relate to these categories of obesity research. Special attention is given to the possible multiple etiologies of obesity and the roles of diet and exercise in weight control. Possible mechanisms underlying inevitable weight regain in reduced obese individuals are discussed relative to cellular and metabolic processes that function in adipose tissue. An hypothesis (termed "the ratchet effect") is offered which suggests than an irreversible increase in adipocytes in some obese subjects may produce increasingly elevated body fat stores that provide a resistance to significant weight reduction. Inferences are drawn for future therapeutic approaches and research directions for obesity attenuation. (wz)
doi_str_mv 10.1111/j.1753-4887.1983.tb07142.x
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ispartof Nutrition reviews, 1983-12, Vol.41 (12), p.361-373
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subjects adipose tissue
Adipose Tissue - metabolism
Adipose Tissue - pathology
Adult
animal experimentation
Animals
Child
Diet, Reducing - standards
Dietary Fats - pharmacology
Dietary Fiber - administration & dosage
Dietary Proteins - administration & dosage
Energy Intake
Female
Humans
Hyperphagia - complications
Infant, Newborn
lipid metabolism
Lipoprotein Lipase - physiology
literature reviews
Male
nutrition research
obesity
Obesity - classification
Obesity - etiology
Obesity - genetics
Obesity - metabolism
Obesity - therapy
Pregnancy
weight loss
title Modern concepts of obesity
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