Effect of Infusions of Osmotically Active Substances on Muscle Blood Flow and Systemic Blood Pressure

To investigate further the action of alterations in plasma osmolarity, the flow through the gastrocnemius-plantaris muscle group and the whole hind leg was measured during close intra-arterial infusions of solutions containing osmotically active substances. The transient and steady-state responses s...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Circulation research 1971-01, Vol.28 (1 Suppl 1), p.33-38
Hauptverfasser: STAINSBY, WENDELL N, BARCLAY, JACK K
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 38
container_issue 1 Suppl 1
container_start_page 33
container_title Circulation research
container_volume 28
creator STAINSBY, WENDELL N
BARCLAY, JACK K
description To investigate further the action of alterations in plasma osmolarity, the flow through the gastrocnemius-plantaris muscle group and the whole hind leg was measured during close intra-arterial infusions of solutions containing osmotically active substances. The transient and steady-state responses showed dilatation during infusion of hypermolal solutions. Some of the transient responses were difficult to explain. Intravenous infusions of hyperosmolal solutions caused an increase in cardiac output, arterial blood pressure, and right atrial pressure and a decrease in resistance to flow through the hind leg. These responses were probably due to constriction of the venous capacitance vessels and dilatation of the precapillary resistance vessels and were caused by some unknown mechanism.
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_80870212</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>80870212</sourcerecordid><originalsourceid>FETCH-LOGICAL-p2517-9403b36fc8de435a0a78c3c8ce5c848c00e173dcc07159b2a1774ab4d70602103</originalsourceid><addsrcrecordid>eNotkFFLwzAUhYMoc05_gpAn3wo3TbK0j3NsOphMmD6XNL1l1bSZTeLYv7fDPl3OOR_34bsiUyZTkQip2DWZAkCeKM7hltx5_wXABE_zCZlIKRhj-ZTgqq7RBOpquunq6BvX-UvY-daFxmhrz3RhQvOLdB9LH3RncAA6-ha9sUifrXMVXVt3orqr6P7sA7aNGfv3Hr2PPd6Tm1pbjw_jnZHP9epj-Zpsdy-b5WKbHFPJVJIL4CWf1yarUHCpQavMcJMZlCYTmQFApnhlDCgm8zLVTCmhS1EpmEPKgM_I0__fY-9-IvpQtI03aK3u0EVfZJCpAUwH8HEEY9liVRz7ptX9uRi9DLv430_OBuz9t40n7IsDahsOxaAVOLA0YbliwAatyaVS_A_BDG7V</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>80870212</pqid></control><display><type>article</type><title>Effect of Infusions of Osmotically Active Substances on Muscle Blood Flow and Systemic Blood Pressure</title><source>MEDLINE</source><source>American Heart Association</source><source>Journals@Ovid Complete</source><source>Free E-Journal (出版社公開部分のみ)</source><creator>STAINSBY, WENDELL N ; BARCLAY, JACK K</creator><creatorcontrib>STAINSBY, WENDELL N ; BARCLAY, JACK K</creatorcontrib><description>To investigate further the action of alterations in plasma osmolarity, the flow through the gastrocnemius-plantaris muscle group and the whole hind leg was measured during close intra-arterial infusions of solutions containing osmotically active substances. The transient and steady-state responses showed dilatation during infusion of hypermolal solutions. Some of the transient responses were difficult to explain. Intravenous infusions of hyperosmolal solutions caused an increase in cardiac output, arterial blood pressure, and right atrial pressure and a decrease in resistance to flow through the hind leg. These responses were probably due to constriction of the venous capacitance vessels and dilatation of the precapillary resistance vessels and were caused by some unknown mechanism.</description><identifier>ISSN: 0009-7330</identifier><identifier>EISSN: 1524-4571</identifier><identifier>PMID: 5541119</identifier><language>eng</language><publisher>United States: American Heart Association, Inc</publisher><subject>Animals ; Arteries ; Blood Flow Velocity ; Blood Pressure - drug effects ; Cardiac Output - drug effects ; Dilatation - drug effects</subject><ispartof>Circulation research, 1971-01, Vol.28 (1 Suppl 1), p.33-38</ispartof><rights>1971 American Heart Association, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/5541119$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>STAINSBY, WENDELL N</creatorcontrib><creatorcontrib>BARCLAY, JACK K</creatorcontrib><title>Effect of Infusions of Osmotically Active Substances on Muscle Blood Flow and Systemic Blood Pressure</title><title>Circulation research</title><addtitle>Circ Res</addtitle><description>To investigate further the action of alterations in plasma osmolarity, the flow through the gastrocnemius-plantaris muscle group and the whole hind leg was measured during close intra-arterial infusions of solutions containing osmotically active substances. The transient and steady-state responses showed dilatation during infusion of hypermolal solutions. Some of the transient responses were difficult to explain. Intravenous infusions of hyperosmolal solutions caused an increase in cardiac output, arterial blood pressure, and right atrial pressure and a decrease in resistance to flow through the hind leg. These responses were probably due to constriction of the venous capacitance vessels and dilatation of the precapillary resistance vessels and were caused by some unknown mechanism.</description><subject>Animals</subject><subject>Arteries</subject><subject>Blood Flow Velocity</subject><subject>Blood Pressure - drug effects</subject><subject>Cardiac Output - drug effects</subject><subject>Dilatation - drug effects</subject><issn>0009-7330</issn><issn>1524-4571</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1971</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNotkFFLwzAUhYMoc05_gpAn3wo3TbK0j3NsOphMmD6XNL1l1bSZTeLYv7fDPl3OOR_34bsiUyZTkQip2DWZAkCeKM7hltx5_wXABE_zCZlIKRhj-ZTgqq7RBOpquunq6BvX-UvY-daFxmhrz3RhQvOLdB9LH3RncAA6-ha9sUifrXMVXVt3orqr6P7sA7aNGfv3Hr2PPd6Tm1pbjw_jnZHP9epj-Zpsdy-b5WKbHFPJVJIL4CWf1yarUHCpQavMcJMZlCYTmQFApnhlDCgm8zLVTCmhS1EpmEPKgM_I0__fY-9-IvpQtI03aK3u0EVfZJCpAUwH8HEEY9liVRz7ptX9uRi9DLv430_OBuz9t40n7IsDahsOxaAVOLA0YbliwAatyaVS_A_BDG7V</recordid><startdate>197101</startdate><enddate>197101</enddate><creator>STAINSBY, WENDELL N</creator><creator>BARCLAY, JACK K</creator><general>American Heart Association, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>197101</creationdate><title>Effect of Infusions of Osmotically Active Substances on Muscle Blood Flow and Systemic Blood Pressure</title><author>STAINSBY, WENDELL N ; BARCLAY, JACK K</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p2517-9403b36fc8de435a0a78c3c8ce5c848c00e173dcc07159b2a1774ab4d70602103</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1971</creationdate><topic>Animals</topic><topic>Arteries</topic><topic>Blood Flow Velocity</topic><topic>Blood Pressure - drug effects</topic><topic>Cardiac Output - drug effects</topic><topic>Dilatation - drug effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>STAINSBY, WENDELL N</creatorcontrib><creatorcontrib>BARCLAY, JACK K</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Circulation research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>STAINSBY, WENDELL N</au><au>BARCLAY, JACK K</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of Infusions of Osmotically Active Substances on Muscle Blood Flow and Systemic Blood Pressure</atitle><jtitle>Circulation research</jtitle><addtitle>Circ Res</addtitle><date>1971-01</date><risdate>1971</risdate><volume>28</volume><issue>1 Suppl 1</issue><spage>33</spage><epage>38</epage><pages>33-38</pages><issn>0009-7330</issn><eissn>1524-4571</eissn><abstract>To investigate further the action of alterations in plasma osmolarity, the flow through the gastrocnemius-plantaris muscle group and the whole hind leg was measured during close intra-arterial infusions of solutions containing osmotically active substances. The transient and steady-state responses showed dilatation during infusion of hypermolal solutions. Some of the transient responses were difficult to explain. Intravenous infusions of hyperosmolal solutions caused an increase in cardiac output, arterial blood pressure, and right atrial pressure and a decrease in resistance to flow through the hind leg. These responses were probably due to constriction of the venous capacitance vessels and dilatation of the precapillary resistance vessels and were caused by some unknown mechanism.</abstract><cop>United States</cop><pub>American Heart Association, Inc</pub><pmid>5541119</pmid><tpages>6</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0009-7330
ispartof Circulation research, 1971-01, Vol.28 (1 Suppl 1), p.33-38
issn 0009-7330
1524-4571
language eng
recordid cdi_proquest_miscellaneous_80870212
source MEDLINE; American Heart Association; Journals@Ovid Complete; Free E-Journal (出版社公開部分のみ)
subjects Animals
Arteries
Blood Flow Velocity
Blood Pressure - drug effects
Cardiac Output - drug effects
Dilatation - drug effects
title Effect of Infusions of Osmotically Active Substances on Muscle Blood Flow and Systemic Blood Pressure
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-28T06%3A45%3A37IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effect%20of%20Infusions%20of%20Osmotically%20Active%20Substances%20on%20Muscle%20Blood%20Flow%20and%20Systemic%20Blood%20Pressure&rft.jtitle=Circulation%20research&rft.au=STAINSBY,%20WENDELL%20N&rft.date=1971-01&rft.volume=28&rft.issue=1%20Suppl%201&rft.spage=33&rft.epage=38&rft.pages=33-38&rft.issn=0009-7330&rft.eissn=1524-4571&rft_id=info:doi/&rft_dat=%3Cproquest_pubme%3E80870212%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=80870212&rft_id=info:pmid/5541119&rfr_iscdi=true