Benzodiazepine receptor ligands with positive and negative efficacy

Recent studies have shown that benzodiazepine receptors can be affected not only by benzodiazepine agonists and antagonists but also by a new class of ligands which produce effects opposite to those of benzodiazepines, that is they produce convulsions and anxiety. These ligands can be described as h...

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Veröffentlicht in:	Neuropharmacology 1983-12, Vol.22 (12), p.1451-1457
Hauptverfasser:	Braestrup, C., Nielsen, M., Honoré, T., Jensen, L.H., Petersen, E.N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acoustic Stimulation Animals Carbolines - metabolism Chlorides - metabolism gamma-Aminobutyric Acid - pharmacology Humans Ligands Receptors, Cell Surface - drug effects Receptors, Cell Surface - metabolism Receptors, GABA-A Seizures - metabolism
Online-Zugang:	Volltext
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