Development of a Babesia rodhaini mouse assay for quality control of the serum component of a bovine babesiosis vaccine

The rodent babesia, Babesia rodhaini, survived equally well in basal medium containing either 10 per cent rat serum or 10 per cent bovine serum. As a result, a B rodhaini mouse assay is now performed routinely to determine the suitability of batches of bovine serum for use in a commercial Babesia bo...

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Veröffentlicht in:Research in veterinary science 1983-11, Vol.35 (3), p.331-333
Hauptverfasser: Timms, P., Rodwell, B.J., Barry, D.N.
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container_issue 3
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container_title Research in veterinary science
container_volume 35
creator Timms, P.
Rodwell, B.J.
Barry, D.N.
description The rodent babesia, Babesia rodhaini, survived equally well in basal medium containing either 10 per cent rat serum or 10 per cent bovine serum. As a result, a B rodhaini mouse assay is now performed routinely to determine the suitability of batches of bovine serum for use in a commercial Babesia bovis vaccine issued in Australia. Heat inactivation of bovine serum at 56°C for two hours did not affect the survival of either B bovis or B rodhaini.
doi_str_mv 10.1016/S0034-5288(18)32028-9
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identifier ISSN: 0034-5288
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source MEDLINE; ScienceDirect Journals (5 years ago - present)
subjects Animals
assays
Babesia - physiology
Babesia bovis
Babesia rodhaini
Babesiosis - prevention & control
Biological and medical sciences
Biological Assay - methods
Cattle
Cattle Diseases - prevention & control
Cell Survival
Experimental protozoal diseases and models
immunization
Infectious diseases
Medical sciences
Mice
Mice, Inbred CBA
Parasitic diseases
Plasma
Protozoal diseases
serum
vaccines
Vaccines - standards
title Development of a Babesia rodhaini mouse assay for quality control of the serum component of a bovine babesiosis vaccine
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