Immunocytochemical detection of carcinoembryonic antigen in salivary gland tumors

The immunoperoxidase method was applied for carcinoembryonic antigen (CEA) detection in biopsy specimens of salivary gland tumors. 9 out of 10 adenoidcystic carcinomas revealed a strong and abundant reaction in tumoral glands. 10 other specimens of pleomorphic adenomas showed weak staining in the ar...

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Veröffentlicht in:	International journal of oral surgery 1983-10, Vol.12 (5), p.340-343
Hauptverfasser:	Itoiz, María E., Lanfranchi, H.E., Cabrini, R.L., Dominguez, F.V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoma, Pleomorphic - analysis antigen, carcinoembryonic Biological and medical sciences cancer, oral Carcinoembryonic Antigen - analysis Carcinoma, Adenoid Cystic - analysis Dentistry Humans immunocytochemistry Immunoenzyme Techniques Medical sciences Otorhinolaryngology. Stomatology Salivary Gland Neoplasms - analysis Salivary Glands - analysis Staining and Labeling tumor, salivary gland Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology
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Zusammenfassung:	The immunoperoxidase method was applied for carcinoembryonic antigen (CEA) detection in biopsy specimens of salivary gland tumors. 9 out of 10 adenoidcystic carcinomas revealed a strong and abundant reaction in tumoral glands. 10 other specimens of pleomorphic adenomas showed weak staining in the areas of epithelial proliferation. Normal glands adjacent to the tumor mass revealed a weak but constant reaction on the luminal border. As in other types of gland tumor, the quantitative estimation of CEA production by salivary gland tumors may be useful in the monitoring of recurrencies.
ISSN:	0300-9785
DOI:	10.1016/S0300-9785(83)80023-4