Comparative effects of FR 34235, a new slow channel calcium blocker, and nifedipine on hemodynamics and myocardial oxygen consumption in the anesthetized dog

1. 1. Five doses of two dihydropyridine calcium antagonists, FR 34235 and nifedipine, were given intravenously to anesthetized dogs to determine effects on hemodynamics and myocardial oxygen balance. 2. 2. Both agents produced dose-related decreases in mean arterial blood pressure and tension time i...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	General pharmacology 1983, Vol.14 (6), p.677-680
Hauptverfasser:	Gross, Garrett J., Warltier, David C., Hardman, Harold F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia Animals Blood Pressure - drug effects Calcium Channel Blockers - pharmacology Coronary Circulation - drug effects Dogs Female Hemodynamics - drug effects Male Myocardium - metabolism Nifedipine - analogs & derivatives Nifedipine - pharmacology Oxygen Consumption - drug effects
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!