Properties of murine anti-morphine antibodies

Properties of murine anti-morphine antibodies

Four lines of high affinity monoclonal antibodies directed against morphine have been isolated and affinity purified. Some of their properties, including cross-reactivities to a large set of selected opiate agonists and antagonists are described. Importantly, none of the immunoglobulins cross-react...

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Veröffentlicht in:Molecular immunology 1983-01, Vol.20 (12), p.1419-1422
Hauptverfasser: Glasel, Jay A., Braudbury, Williams M., Venn, Richard F.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Antibodies, Monoclonal - immunology
Biological and medical sciences
Cell physiology
Chromatography, Affinity
Cross Reactions
Enkephalin, Leucine - analogs & derivatives
Enkephalin, Leucine - immunology
Enkephalin, Leucine-2-Alanine
Female
Fundamental and applied biological sciences. Psychology
Immunoglobulin G - immunology
Mice
Mice, Inbred BALB C
Molecular and cellular biology
monoclonal antibodies
morphine
Morphine - immunology
Narcotic Antagonists - immunology
Neurotransmission
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Zusammenfassung:Four lines of high affinity monoclonal antibodies directed against morphine have been isolated and affinity purified. Some of their properties, including cross-reactivities to a large set of selected opiate agonists and antagonists are described. Importantly, none of the immunoglobulins cross-react with D-Ala 2-D-Leu 5-enkephal
ISSN:0161-5890
1872-9142
DOI:10.1016/0161-5890(83)90175-X