A dominantly inherited cytogenetic anomaly: a possible cell division mutant

Short-term lymphocyte cultures from three unrelated patients showed an increased frequency of mitoses with separated centromeres and splayed chromatids in the presence of colcemid. We refer to this phenomenon as premature centromere division (PCD). In two of the three patients the frequency of PCD i...

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Veröffentlicht in:	Human genetics 1983-12, Vol.65 (2), p.117-121
Hauptverfasser:	RUDD, N. L, TESHIMA, I. E, MARTIN, R. H, SISKEN, J. E, WEKSBERG, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Abortion, Spontaneous - genetics Adult Biological and medical sciences Cell Division Centromere - ultrastructure Chromatids - ultrastructure Chromosomes - ultrastructure Cytogenetics Female Fibroblasts - ultrastructure Fundamental and applied biological sciences. Psychology Genes, Dominant Genetics of eukaryotes. Biological and molecular evolution Human Humans Lymphocytes - ultrastructure Male Metaphase Mitosis Mutation Polyploidy Pregnancy
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