Activation of Factor XII in Human Plasma: Protection by Benzamidine of the Cofactor Function of High Molecular Weight Kininogen

: By incubation of human citrated plasma with acetone 25% v/v kallikrein inhibitors were destroyed and prekallikrein activated to kallikrein. When the incubation was carried out in the presence of benzamidine 7 mM, the cofactor capacity of high molecular weight kininogen (HMrK) was protected against...

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Veröffentlicht in:	Acta pharmacologica et toxicologica 1983-10, Vol.53 (4), p.344-352
Hauptverfasser:	Briseid, Kjell, Johansen, Harald Thidemann
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Amidines - pharmacology benzamidine Benzamidines - pharmacology Biological and medical sciences Blood coagulation. Blood cells Coagulation factors Factor XII Factor XII - physiology Female Fundamental and applied biological sciences. Psychology high molecular weight kininogen Humans Kininogens - physiology Male Middle Aged Molecular and cellular biology Molecular Weight plasminogen activator Plasminogen Activators - physiology Prekallikrein - physiology
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