Studies on Benzhydryl Derivatives. IV. Synthesis and Anti-inflammatory Activity of 2-O-(Diphenylacetyl)salicylic Acids

A synthetic route to 2-O-(diphenylacetyl)salicylic acid derivatives was developed and the effects of the products on the heat-denaturation of albumin and on heat-induced erythrocytolysis were examined (in vitro anti-inflammation test). Trichloroethyl salicylate was acylated with diphenylacetic acid...

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Veröffentlicht in:	Chemical & pharmaceutical bulletin 1983/08/25, Vol.31(8), pp.2632-2638
Hauptverfasser:	TAKEMURA, SHOJI, AZUMA, YOSHIKO, SHOGAKI, CHIYUKI, MIKI, YASUYOSHI, NAGATOMI, HIKARU, YASUI, BOMPEI, ANDO, KAZUKO
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents - chemical synthesis anti-inflammatory assay in vitro Aspirin - analogs & derivatives Aspirin - chemical synthesis Aspirin - pharmacology Chemistry Erythrocytes - drug effects Exact sciences and technology In Vitro Techniques Noncondensed benzenic compounds Organic chemistry Preparations and properties Rats
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