Brain Peptides: What, Where, and Why?
Within the past decade, a large number of peptides have been described within the vertebrate central nervous system. Some of these peptides were previously known to be present in nonneural vertebrate tissues, as well as in lower species, in which they may serve as primitive elements of intercellular...
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| Veröffentlicht in: | Science (American Association for the Advancement of Science) 1983-12, Vol.222 (4627), p.975-985 |
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| container_title | Science (American Association for the Advancement of Science) |
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| creator | Krieger, Dorothy T. |
| description | Within the past decade, a large number of peptides have been described within the vertebrate central nervous system. Some of these peptides were previously known to be present in nonneural vertebrate tissues, as well as in lower species, in which they may serve as primitive elements of intercellular communication prior to the development of neuronal or endocrine systems. In vertebrates, these peptides are thought to have neurotransmitter or neuromodulatory roles and appear to be involved in the regulation of a number of homeostatic systems, although the mechanisms of their actions are still unclear. |
| doi_str_mv | 10.1126/science.6139875 |
| format | Article |
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Some of these peptides were previously known to be present in nonneural vertebrate tissues, as well as in lower species, in which they may serve as primitive elements of intercellular communication prior to the development of neuronal or endocrine systems. 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Pathways and receptors ; Endocrinology, Experimental ; Feeding Behavior - physiology ; Fundamental and applied biological sciences. Psychology ; Hormones ; Humans ; Invertebrates - metabolism ; Learning - physiology ; Memory - physiology ; Molecules ; Nerve tissue ; Nerve Tissue Proteins - analysis ; Nerve Tissue Proteins - physiology ; Neurons ; Neurotransmitter Agents - analysis ; Neurotransmitter Agents - physiology ; Neurotransmitters ; Opioid analgesics ; Pain - physiopathology ; Peptides ; Physiological aspects ; Pituitary Hormones, Anterior - metabolism ; Pro-Opiomelanocortin ; Protein Precursors - metabolism ; Protein Processing, Post-Translational ; Receptors, Neurotransmitter - metabolism ; Schizophrenia - physiopathology ; Vertebrates ; Vertebrates: nervous system and sense organs</subject><ispartof>Science (American Association for the Advancement of Science), 1983-12, Vol.222 (4627), p.975-985</ispartof><rights>Copyright 1983 The American Association for the Advancement of Science</rights><rights>1984 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c470t-78983b5f2dea6312772b29be6493cb13857bdb3ab6c526cc456d525c2b51bbef3</citedby><cites>FETCH-LOGICAL-c470t-78983b5f2dea6312772b29be6493cb13857bdb3ab6c526cc456d525c2b51bbef3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/1691252$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/1691252$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>314,777,781,800,2872,2873,27906,27907,57999,58232</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=9368339$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6139875$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Krieger, Dorothy T.</creatorcontrib><title>Brain Peptides: What, Where, and Why?</title><title>Science (American Association for the Advancement of Science)</title><addtitle>Science</addtitle><description>Within the past decade, a large number of peptides have been described within the vertebrate central nervous system. Some of these peptides were previously known to be present in nonneural vertebrate tissues, as well as in lower species, in which they may serve as primitive elements of intercellular communication prior to the development of neuronal or endocrine systems. In vertebrates, these peptides are thought to have neurotransmitter or neuromodulatory roles and appear to be involved in the regulation of a number of homeostatic systems, although the mechanisms of their actions are still unclear.</description><subject>Amino acids</subject><subject>Animals</subject><subject>Biochemistry</subject><subject>Biological and medical sciences</subject><subject>Biological Evolution</subject><subject>Blood Pressure</subject><subject>Body Temperature Regulation</subject><subject>Brain</subject><subject>Brain - metabolism</subject><subject>Brain Chemistry</subject><subject>Brain Diseases - metabolism</subject><subject>Central nervous system</subject><subject>Central neurotransmission. Neuromudulation. Pathways and receptors</subject><subject>Endocrinology, Experimental</subject><subject>Feeding Behavior - physiology</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Hormones</subject><subject>Humans</subject><subject>Invertebrates - metabolism</subject><subject>Learning - physiology</subject><subject>Memory - physiology</subject><subject>Molecules</subject><subject>Nerve tissue</subject><subject>Nerve Tissue Proteins - analysis</subject><subject>Nerve Tissue Proteins - physiology</subject><subject>Neurons</subject><subject>Neurotransmitter Agents - analysis</subject><subject>Neurotransmitter Agents - physiology</subject><subject>Neurotransmitters</subject><subject>Opioid analgesics</subject><subject>Pain - physiopathology</subject><subject>Peptides</subject><subject>Physiological aspects</subject><subject>Pituitary Hormones, Anterior - metabolism</subject><subject>Pro-Opiomelanocortin</subject><subject>Protein Precursors - metabolism</subject><subject>Protein Processing, Post-Translational</subject><subject>Receptors, Neurotransmitter - metabolism</subject><subject>Schizophrenia - physiopathology</subject><subject>Vertebrates</subject><subject>Vertebrates: nervous system and sense organs</subject><issn>0036-8075</issn><issn>1095-9203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1983</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkT1PwzAQhi0EglKYWUDqACwQsH2xE7MgqPiSKpUBxGjZzgWC0qTYqUT_Pa4awcjis_Q-9_HeEXLA6AVjXF4GV2Hj8EIyUHkmNsiAUSUSxSlskgGlIJOcZmKH7IbwSWnUFGyT7R4fkJNbb6pm9IzzriowXI3ePkx3Hl_0eD4yTRG_y-s9slWaOuB-H4fk9f7uZfyYTKYPT-ObSeLSjHZJlqscrCh5gUYC41nGLVcWZarAWQa5yGxhwVjpBJfOpUIWggvHrWDWYglDcrquO_ft1wJDp2dVcFjXpsF2EXS0oqjKxL8gB0ZzSNN_wThUGne1qni2Bt9NjbpqXNt0-N25tq7xHXW0OZ7qG6CgRHQzJJdr2vk2BI-lnvtqZvxSM6pXh9H9YXS_6Zhx1A-ysDMsfvk__bjXTXCmLr1pXBV-MQUyB1g1Plxjn6Fr_V9XqRgXHH4AGACcfA</recordid><startdate>19831202</startdate><enddate>19831202</enddate><creator>Krieger, Dorothy T.</creator><general>The American Association for the Advancement of Science</general><general>American Association for the Advancement of Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>8FD</scope><scope>H8D</scope><scope>L7M</scope><scope>7X8</scope></search><sort><creationdate>19831202</creationdate><title>Brain Peptides: What, Where, and Why?</title><author>Krieger, Dorothy T.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c470t-78983b5f2dea6312772b29be6493cb13857bdb3ab6c526cc456d525c2b51bbef3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1983</creationdate><topic>Amino acids</topic><topic>Animals</topic><topic>Biochemistry</topic><topic>Biological and medical sciences</topic><topic>Biological Evolution</topic><topic>Blood Pressure</topic><topic>Body Temperature Regulation</topic><topic>Brain</topic><topic>Brain - metabolism</topic><topic>Brain Chemistry</topic><topic>Brain Diseases - metabolism</topic><topic>Central nervous system</topic><topic>Central neurotransmission. Neuromudulation. Pathways and receptors</topic><topic>Endocrinology, Experimental</topic><topic>Feeding Behavior - physiology</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Hormones</topic><topic>Humans</topic><topic>Invertebrates - metabolism</topic><topic>Learning - physiology</topic><topic>Memory - physiology</topic><topic>Molecules</topic><topic>Nerve tissue</topic><topic>Nerve Tissue Proteins - analysis</topic><topic>Nerve Tissue Proteins - physiology</topic><topic>Neurons</topic><topic>Neurotransmitter Agents - analysis</topic><topic>Neurotransmitter Agents - physiology</topic><topic>Neurotransmitters</topic><topic>Opioid analgesics</topic><topic>Pain - physiopathology</topic><topic>Peptides</topic><topic>Physiological aspects</topic><topic>Pituitary Hormones, Anterior - metabolism</topic><topic>Pro-Opiomelanocortin</topic><topic>Protein Precursors - metabolism</topic><topic>Protein Processing, Post-Translational</topic><topic>Receptors, Neurotransmitter - metabolism</topic><topic>Schizophrenia - physiopathology</topic><topic>Vertebrates</topic><topic>Vertebrates: nervous system and sense organs</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Krieger, Dorothy T.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>Technology Research Database</collection><collection>Aerospace Database</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>MEDLINE - Academic</collection><jtitle>Science (American Association for the Advancement of Science)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Krieger, Dorothy T.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Brain Peptides: What, Where, and Why?</atitle><jtitle>Science (American Association for the Advancement of Science)</jtitle><addtitle>Science</addtitle><date>1983-12-02</date><risdate>1983</risdate><volume>222</volume><issue>4627</issue><spage>975</spage><epage>985</epage><pages>975-985</pages><issn>0036-8075</issn><eissn>1095-9203</eissn><coden>SCIEAS</coden><abstract>Within the past decade, a large number of peptides have been described within the vertebrate central nervous system. Some of these peptides were previously known to be present in nonneural vertebrate tissues, as well as in lower species, in which they may serve as primitive elements of intercellular communication prior to the development of neuronal or endocrine systems. In vertebrates, these peptides are thought to have neurotransmitter or neuromodulatory roles and appear to be involved in the regulation of a number of homeostatic systems, although the mechanisms of their actions are still unclear.</abstract><cop>Washington, DC</cop><pub>The American Association for the Advancement of Science</pub><pmid>6139875</pmid><doi>10.1126/science.6139875</doi><tpages>11</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0036-8075 |
| ispartof | Science (American Association for the Advancement of Science), 1983-12, Vol.222 (4627), p.975-985 |
| issn | 0036-8075 1095-9203 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_80790975 |
| source | MEDLINE; American Association for the Advancement of Science; Jstor Complete Legacy |
| subjects | Amino acids Animals Biochemistry Biological and medical sciences Biological Evolution Blood Pressure Body Temperature Regulation Brain Brain - metabolism Brain Chemistry Brain Diseases - metabolism Central nervous system Central neurotransmission. Neuromudulation. Pathways and receptors Endocrinology, Experimental Feeding Behavior - physiology Fundamental and applied biological sciences. Psychology Hormones Humans Invertebrates - metabolism Learning - physiology Memory - physiology Molecules Nerve tissue Nerve Tissue Proteins - analysis Nerve Tissue Proteins - physiology Neurons Neurotransmitter Agents - analysis Neurotransmitter Agents - physiology Neurotransmitters Opioid analgesics Pain - physiopathology Peptides Physiological aspects Pituitary Hormones, Anterior - metabolism Pro-Opiomelanocortin Protein Precursors - metabolism Protein Processing, Post-Translational Receptors, Neurotransmitter - metabolism Schizophrenia - physiopathology Vertebrates Vertebrates: nervous system and sense organs |
| title | Brain Peptides: What, Where, and Why? |
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