Identification of proopiomelanocortin neurones in rat hypothalamus by in situ cDNA-mRNA hybridization

Ardrenocorticotropic hormone (ACTH), β -endorphin and the melanotropins (MSHs) are all derived from a single large precursor molecule, proopiomelanocortin (POMC) 1–5 by individual processing through a series of co- and post-translational modifications. Although the primary site of synthesis is in th...

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