Solid-State Decomposition of Alkoxyfuroic Acids in the Presence of Microcrystalline Cellulose

□ A solid-solid interaction between alkoxyfuroic acids and microcrystalline cellulose has been studied. The decomposition of the mixture differs from that of the drug(s) alone, in that carbon monoxide (not carbon dioxide) is the high-temperature decomposition product. A model is proposed in which in...

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Veröffentlicht in:	Journal of pharmaceutical sciences 1983-10, Vol.72 (10), p.1149-1154
Hauptverfasser:	Carstensen, J.T., Kothari, Rohit C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkoxyfuroic acid-solid-state interactions with microcrystalline cellulose Alkoxyfuroic acid—solid-state interactions with microcrystalline cellulose, decomposition model Biological and medical sciences Cellulose Chemistry, Pharmaceutical decomposition model Decomposition-alkoxyfuroic acids with microcrystalline cellulose Decomposition—alkoxyfuroic acids with microcrystalline cellulose, model, solid-state interactions Drug Incompatibility Drug Stability Excipients Furans General pharmacology Medical sciences Microcrystalline cellulose-solid-state interactions with alkoxyfuroic acids Microcrystalline cellulose—solid-state interactions with alkoxyfuroic acids, decomposition model Models, Chemical Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments solid-state interactions Temperature
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